TITLE

Radiopharmaceuticals for the Visualization of Infectious and Inflammatory Lesions

AUTHOR(S)
Ercan, Meral Tayan; Kostakoglu, Lale
PUB. DATE
July 2000
SOURCE
Current Pharmaceutical Design;Jul2000, Vol. 6 Issue 11, p1159
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Many radiopharmaceuticals have been introduced for the scintigraphic demonstration of infectious and inflammatory lesions and some of them are currently in clinical use. They can be classified into two major categories according to their specificity. Specific radiopharmaceuticals include in vitro labeled leukocytes, radio-labelled monoclonal antibodies, and receptor specific small proteins and peptides. Nonspecific radiopharmaceuticals include radiolabelled nanocolloids, liposomes, macromolecules such as human immunoglobulin, dextran and human serum albumin, various small molecules and ions. In this review article radiopharmaceuticals in their respective groups are discussed as to the efficacy, and other parameters such as the physical characteristics of the radionuclides used, radiochemistry involved, availability, cost and biodistribution, emphasizing recent developments.
ACCESSION #
11134253

 

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