A novel mutation in ferroportin 1 is associated with haemochromatosis in a Solomon Islands patient
- Too much iron--risky for young and old. // Environmental Nutrition;Apr97, Vol. 20 Issue 4, p3
Discusses the risks of iron overdose. Dangers of accidental iron overdose in children; Definition and nature of hereditary hemochromatosis (iron overload) in adults; Importance of measuring the total iron binding capacity (TIBC) before taking iron-containing supplements; Treatment for...
- Get the Iron Out: A Simple Solution To a Serious Problem. Dunkin, Mary Anne // Arthritis Today;Sep/Oct99, Vol. 13 Issue 5, p14
Provides information on hemochromatosis, a chronic disease that occurs when a glitch in the body's metabolism causes absorption of too much iron from foods. Problems caused by the iron deposits in extreme cases; Recommendation to avoid the disease.
- Mining the genome for iron. Kaplan, Jerry; Kushner, James P. // Nature;2/17/2000, Vol. 403 Issue 6771, p711
Reports on the identification of the transporters responsible for absorption of iron into the enterocytes. Genes involved in regulating intestinal iron absorption; Identification of iron exporter to lead to a better understanding of hereditary hemochromatosis.
- The shocking truth about iron. Finch, Steven // Health (Time Inc. Health);Mar/Apr96, Vol. 10 Issue 2, p116
Discusses the health risks arising from too much iron intake. Roberta Crawford's formation of the Iron Overload Diseases Association in 1981; Focus on hemochromatosis as the most common underdiagnosed genetic disease in the United States; Symptoms; Importance of early diagnosis; Doctors'...
- Duodenal expression of iron transport molecules in untreated haemochromatosis subjects. Stuart, K.A.; Anderson, G.J.; Frazer, D.M.; Powell, L.W.; McCullen, M.; Fletcher, L.M.; Crawford, D.H.G. // Gut;Jul2003, Vol. 52 Issue 7, p953
Background and aims: In HFE associated hereditary haemochromatosis, the duodenal enterocyte behaves as if iron deficient and previous reports have shown increased duodenal expression of divalent metal transporter 1 (DMT1) and iron regulated gene 1 (Ireg1) in affected subjects. In those studies,...
- Lessons from liver transplantation: flip, flop, and why? Adams, P.C. // Gut;Mar2003, Vol. 52 Issue 3, p318
Presents a case of hereditary hemochromatosis developing in a non-hereditary hemochromatosis recipient following transplantation of a C282Y heterozygous donor liver. Widespread application of liver transplantation; Iron accumulation following liver transplantation.
- Heterozygous recipient and donor HFE mutations associated with a hereditary haemochromatosis phenotype after liver transplantation. Wigg, A.J.; Harley, H.; Casey, G. // Gut;Mar2003, Vol. 52 Issue 3, p433
We observed the development of phenotypic hereditary haemochromatosis in a non-hereditary haemochromatosis liver transplant recipient, following transplantation with a liver from a C282Y heterozygous donor. No cause for secondary iron overload was identified. Subsequent sequencing of the HFE...
- Haemochromatosis. Pietrangelo, A. // Gut;May2003 Supplement 2, Vol. 52, pIi23
Iron is an important component of the Earth's crust, but its own chemistry greatly limits utilization and also sets the basis for its toxicity. The capacity of readily exchanging electrons in aerobic conditions makes iron essential for fundamental cell functions, such as DNA synthesis, transport...
- Higher Iron Levels Linked to Diabetes. // Tufts University Health & Nutrition Letter;Apr2004, Vol. 22 Issue 2, p2
Focuses on the link between hemochromatosis, a genetic condition that causes extremely high levels of iron in the body and the risk for developing diabetes in women. Problems caused by excess iron in the body; Effect of high levels of ferritin in the blood of women on the risk of developing...