Tumour necrosis factor Î± is an important mediator of portal and systemic haemodynamic derangements in alcoholic hepatitis
- TNF. // Encyclopedic Reference of Molecular Pharmacology;2004, p911
An encyclopedia entry for "TNS" is presented, which refers to tumor necrosis factor.
- Cytokine anniversary: TNF trailblazers five centuries apart. Libert, Claude // Nature;7/9/2015, Vol. 523 Issue 7559, p158
A letter to the editor is presented concerning the 40th anniversary of a scientific paper that described the discovery of the cell-signalling protein known as tumour necrosis factor (TNF) in the inflammatory disease a cytokine.
- cytokine storm. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p571
A definition of the term "cytokine storm" is presented, which refers to the massive release of interleukins, tumor necrosis factor alpha and other mediators of inflammation that also trigger bleeding, clotting or shock.
- Suppressed Alloantigen Presentation, Increased TNF-Î±, IL-1, IL-1Ra, IL-10, and Modulation of TNF-R in UV-Irradiated Human Skin. Barr, Robert M.; Walker, Susan L.; Tsang, Wailin; Harrison, Graham I.; Ettehadi, Parisa; Greaves, Malcolm W.; Young, Antony R. // Journal of Investigative Dermatology;May99, Vol. 112 Issue 5, p692
Cytokines induced in skin by ultraviolet radiation cause local and systemic immunosuppression. Tumor necrosis factor Î±, interleukin-1, and interleukin-10 are key mediators in the mouse, but less is known about cytokine synthesis and function in ultraviolet-irradiated human skin. We exposed...
- Cytokines and particle-induced inflammatory cell recruitment. Driscoll, Kevin E.; Carter, Janet M.; Hassenbein, Diana G.; Howard, Brian // Environmental Health Perspectives Supplements;Sep97 Supplement 5, Vol. 105, p1159
Summarizes some of the evidence indicating a key role for the cytokine tumor necrosis factor alpha (TNF-alpha) as well as members of the cytokine family in particle-induced inflammation in the lung. Background on tumor necrosis factor; Two branches of the chemokine family; Epithelial cells and...
- Identification of NF-?B-regulated genes induced by TNFa utilizing expression profiling and RNA interference. Zhou, Anwu; Scoggin, Shane; Gaynor, Richard B; Williams, Noelle Sevilir // Oncogene;4/3/2003, Vol. 22 Issue 13, p2054
Tumor necrosis factor a (TNFa) is a proinflammatory cytokine with important roles in regulating inflammatory responses as well as cell cycle proliferation and apoptosis. Although TNFa stimulates apoptosis, it also activates the transcription factor NF-?B, and studies have shown that inhibition...
- TUMOUR NECROSIS FACTOR ALPHA MEDIATES RESISTANCE TO CRYPTOSPORIDIUM PARVUM INFECTION IN ENTEROCYTE CELL LINES BUT IS NOT REQUIRED FOR PROTECTION IN A MOUSE MODEL OF INFECTION. Lean, I.S.; McDonald, S.A.C.; McDonald, V. // Gut;Apr2003 Supplement 1, Vol. 52, pA56
Introduction: It has been suggested that TNF-Î± may play a role in immunity to infection by the intracellular parasite C parvum. Increased mucosal expression of this pro-inflammatory cytokine has been noted in the intestine of infected mice and humans whilst exogenous TNFÎ± has been shown to...
- Vaccinia virus-regulated acute phase cytokine production in human fibroblasts, U937 cells and endothelium. Rokita, H.; Kupiec, T.; Guzik, K.; Koj, A. // Mediators of Inflammation;Apr98, Vol. 7 Issue 2, p73
THE production of acute phase cytokines, interleukin 6 (IL-6), tumour necrosis factor (TNF alpha ) and interleukin 1 (IL-1 beta ), was studied in primary cultures of human skin fibroblasts, human monocytic cell line U937 and primary cultures of human umbilical vein endothelial cells (HUVEC)...
- The effect of high dose digoxin on cytokines in healthy dogs. D�lger, Haluk; Sekeroglu, Mehmet Ramazan; Eryonucu, Beyhan; Noyan, Tevfik; Alici, S�leyman // Mediators of Inflammation;Aug2002, Vol. 11 Issue 4, p261
Background: Tumor necrosis factor (TNF)-a and interleukin (IL)-1ï¿½ are pro-inflammatory cytokines, causing myocardial dysfunction and a negative inotropic effect. The drugs used to treat heart failure affect the production of cytokines. Digoxin, on which this study was focused, is one of the...