Liver tolerance mediated by antigen presenting cells: fact or fiction?

Lau, A.H.; de Creus, A.; Lu, L.; Thomson, A.W.
August 2003
Gut;Aug2003, Vol. 52 Issue 8, p1075
Academic Journal
Discusses the debate on possible on possible mechanisms by which liver antigen presenting cells (APC) may facilitate tolerance induction. Factors influencing the facilitation of tolerance; Contribution of APC to the extensive apoptosis of systemically activated T cells within the liver; Evolution of the telogenic properties of the liver; Role of the hepatic microenvironment rich in interleukin-10 in the promotion of tolerance.


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