More than a vein hope

Brown, Julia
September 2003
Engineer (00137758);9/26/2003, Vol. 292 Issue 7636, p6
Reports that a prototype of the first bio-nano motor is underdevelopment at Rutgers, the state university of New Jersey. Creation of a device that can travel in the human bloodstream and perform a linear opening and closing motion; Use of protein molecules derived from viruses to build the motor; Amount of grant donated by the National Science Foundation.


Related Articles

  • Ultrafast force-clamp spectroscopy of single molecules reveals load dependence of myosin working stroke. Capitanio, Marco; Canepari, Monica; Maffei, Manuela; Beneventi, Diego; Monico, Carina; Vanzi, Francesco; Bottinelli, Roberto; Pavone, Francesco Saverio // Nature Methods;Oct2012, Vol. 9 Issue 10, p1013 

    We describe a dual-trap force-clamp configuration that applies constant loads between a binding protein and an intermittently interacting biological polymer. The method has a measurement delay of only ?10 ?s, allows detection of interactions as brief as ?100 ?s and probes sub-nanometer...

  • Biomolecular/solid-state nanoheterostructures. Douglas, Kenneth; Clark, Noel A.; Rothschild, Kenneth J. // Applied Physics Letters;2/12/1990, Vol. 56 Issue 7, p692 

    We demonstrate a fabrication process for making composite biological/solid-state heterostructures of nanometer dimension (nanoheterostructures). In this process individual protein molecules selectively self-assemble onto a 1.2-nm-thick Ta/W oxide film which has been patterned into a screen-like...

  • Recent Advances and Patents on Solid Lipid Nanoparticles. Sawant, Krutika K.; Dodiya, Shamsunder S. // Recent Patents on Drug Delivery & Formulation;Jun2008, Vol. 2 Issue 2, p120 

    Solid Lipid Nanoparticles (SLNs) have attracted increasing scientific and commercial attention as colloidal drug carriers during the last decade. They have emerged as a potential alternative compared to other colloidal systems like polymeric nanoparticles, liposomes and fat emulsions, as they...

  • Material witness: Cluster control. Ball, Philip // Nature Materials;Mar2012, Vol. 11 Issue 3, p185 

    The article presents a study that investigates the process of making highly concentrated solutions of proteins. It is mentioned that preparing such potent solution is not easy because proteins develop high viscosities at high concentrations, making injection impossible. It is suggested to make...

  • Microbial polyhydroxyalkanote synthesis repression protein PhaR as an affinity tag for recombinant protein purification. Shuang Zhang; Zhi Hui Wang; Guo Qiang Chen // Microbial Cell Factories;2010, Vol. 9, p28 

    Background: PhaR which is a repressor protein for microbial polyhydroxyalkanoates (PHA) biosynthesis, is able to attach to bacterial PHA granules in vivo, was developed as an affinity tag for in vitro protein purification. Fusion of PhaRtagged self-cleavable Ssp DnaB intein to the N-terminus of...

  • Nanomechanics of functional and pathological amyloid materials. Knowles, Tuomas P. J.; Buehler, Markus J. // Nature Nanotechnology;Aug2011, Vol. 6 Issue 8, p469 

    Amyloid or amyloid-like fibrils represent a general class of nanomaterials that can be formed from many different peptides and proteins. Although these structures have an important role in neurodegenerative disorders, amyloid materials have also been exploited for functional purposes by...

  • Generation of protein lattices by fusing proteins with matching rotational symmetry. Sinclair, John C.; Davies, Karen M.; Vénien-Bryan, Catherine; Noble, Martin E. M. // Nature Nanotechnology;Sep2011, Vol. 6 Issue 9, p558 

    The self-assembly of supramolecular structures that are ordered on the nanometre scale is a key objective in nanotechnology. DNA and peptide nanotechnologies have produced various two- and three-dimensional structures, but protein molecules have been underexploited in this area of research. Here...

  • Tunable non-equilibrium gating of flexible DNA nanochannels in response to transport flux. Youdong Mao; Song Chang; Shaoxuan Yang; Qi Ouyang; Lei Jiang // Nature Nanotechnology;Jun2007, Vol. 2 Issue 6, p366 

    Biological nanochannels made from proteins play a central role in cellular signalling. The rapid emergence of DNA nanotechnology in recent years has opened up the possibility of making similar nanochannels from DNA. Building on previous work on switchable DNA nanocompartment, we have constructed...

  • An index for characterization of nanomaterials in biological systems. Xin-Rui Xia; Monteiro-Riviere, Nancy A.; Riviere, Jim E. // Nature Nanotechnology;Sep2010, Vol. 5 Issue 9, p671 

    In a physiological environment, nanoparticles selectively absorb proteins to form ‘nanoparticle–protein coronas’, a process governed by molecular interactions between chemical groups on the nanoparticle surfaces and the amino-acid residues of the proteins. Here, we propose a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics