TITLE

Severe idiopathic gastroparesis due to neuronal and interstitial cells of Cajal degeneration: pathological findings and management

AUTHOR(S)
Zárate, N.; Mearin, F.; Wang, X-Y.; Hewlett, B.; Huizinga, J.D.; Malagelada, J-R.
PUB. DATE
July 2003
SOURCE
Gut;Jul2003, Vol. 52 Issue 7, p966
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Delayed gastric emptying can be due to muscular, neural, or humoral abnormalities. In the absence of an identified cause, gastroparesis is labelled as idiopathic. We present the case of a patient with severe idiopathic gastroparesis. Pharmacological approaches failed, as well as reduction in gastric emptying resistance with pyloric injection of botulinum toxin and pyloroplasty. Therefore, subtotal gastrectomy was performed. Histological and immunohistochemical study of the resected specimen showed hypoganglionosis, neuronal dysplasia, and a marked reduction in both myenteric and intramuscular interstitial cells of Cajal. To our knowledge, this is the first time these rare histological findings have been described in a patient with idiopathic gastroparesis.
ACCESSION #
10998100

 

Related Articles

  • When Diabetes Leads to a Lazy Stomach: The Goods on Gastroparesis. Von Wartburg, Linda // Diabetes Health;Oct/Nov2007, Vol. 16 Issue 5, p21 

    The article offers information on gastroparesis. Also known as stomach paralysis, gastroparesis is a kind of diabetic neuropathy or nerve damage. Its symptoms include bloating, abdominal pain, nausea, feeling full after just a few bites of a meal, weight loss and heartburn. Making dietary...

  • gastroparalysis.  // Taber's Cyclopedic Medical Dictionary;2005, p860 

    A definition of the medical term "gastroparalysis" is presented, which refers to the paralysis of the stomach.

  • Stomach pain: What's serious, what's not. Heller, Linda // Redbook;Oct95, Vol. 185 Issue 6, p30 

    Lists symptoms of serious stomachache that need to be consulted to a doctor. Includes severe pain; Presence of fever; Presence of blood in stool.

  • Isolated Gastric Tuberculosis: A Case Report and Review of Literature. Mukhopadhyay, Madhumita; Rahaman, Quazi; Mallick, Nisith; Khan, Dawood; Roy, Sudipta; Biswas, Niloy // Indian Journal of Surgery;Oct2010, Vol. 72 Issue 5, p412 

    Isolated gastric tuberculosis is a rare condition, even in those parts of the world where intestinal tuberculosis is common. Herein we describe a case of a thirty year old female patient with isolated gastric tuberculosis who presented with features of gastric outlet obstruction.

  • Remedies for Revelers: 5 essential stomach soothers.  // Homeopathy Today;Winter2016, Vol. 36 Issue 4, p42 

    The article presents the several indispensible homeopathic remedies to have on hand for the winter and New Year festivities including pulsatilla, lycopodium and nux vomica.

  • ooooh! My Stomach Hurts! Gard, Carolyn // Current Health 1;Oct2002, Vol. 26 Issue 2, p20 

    Provides information on the different causes of stomach pain in children, including gastroenteritis.

  • Gastric cancer, diet, and nitrate exposure. Forman, David // British Medical Journal (Clinical Research Edition);2/28/1987, Vol. 294 Issue 6571, p528 

    Focuses on the incidence of gastric cancer in Great Britain. Role of dietary practice in the outbreak of the disease; Phases of gastric carcinogenesis; Advice of the government to increase consumption of foods with vitamin C.

  • Clinicopathologic significance of sialyl Le xexpression in advanced gastric carcinoma. Futamura, N; Nakamura, S; Tatematsu, M; Yamamura, Y; Kannagi, R; Hirose, H // British Journal of Cancer;12/15/2000, Vol. 83 Issue 12, p1681 

    Sialyl Lewis[SUPx] antigen (SLX) is a carbohydrate antigen that serves as a ligand for selectin, an adhesion molecule expressed on vascular endothelial cells. The expression of SLX in 245 patients with advanced gastric carcinoma was examined immunohistochemically, and its clinicopathologic...

  • Estrogen's protective affect for gastric cancer? Lemon, Thomas Iain; Lee, Annabelle // International Journal of Students' Research;2013, Vol. 3 Issue 2, p61 

    A letter to the editor is presented in response to the article "Gastric Cancer in Young People Under 30 Years of Age: Worse Prognosis, or Delay in Diagnosis?" in the 2013 issue.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics