TITLE

The dendritic cell: its role in intestinal inflammation and relationship with gut bacteria

AUTHOR(S)
Stagg A J; Hart A L; Knight S C; Kamm M A
PUB. DATE
October 2003
SOURCE
Gut;Oct2003, Vol. 52 Issue 10, p1522
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Dendritic cells are antigen presenting cells that are likely to be pivotal in the balance between tolerance and active immunity to commensal microorganisms that is fundamental to inflammatory conditions, including Crohn's disease and ulcerative colitis. Interactions between dendritic cells and microbial products are discussed and how they contribute to regulation of immune responses. The concept that interactions between dendritic cells and commensal organisms may be responsible for maintaining intestinal immune homeostasis is also explored.
ACCESSION #
10854359

 

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