Oxygen supplementation before or after submaximal exercise in patients with chronic obstructive pulmonary disease

Nandi K; Smith A A; Crawford A; MacRae K D; Garrod R; Seed W A; Roberts C M
August 2003
Thorax;Aug2003, Vol. 58 Issue 8, p670
Academic Journal
BACKGROUND: Evidence for improved exercise tolerance or relief of breathlessness by short term use of oxygen before or after exercise in patients with chronic obstructive pulmonary disease (COPD) is scant, and guidelines for this treatment are lacking despite widespread provision in the UK. METHODS: The effect of oxygenation either before or after exercise on perception of breathlessness and walk distance was studied in a group of patients with moderate to severe COPD (mean forced expiratory volume in 1 second (FEV(1)) 34% of predicted, mean 6 minute walk distance on air 283 m), all of whom desaturated by at least 4% on submaximal exercise. Oxygen (28%) or air was delivered double blind and in random order, either for 5 minutes before a standard 6 minute walk test (n=34) or for 5 minutes following the end of the test (n=18). Exercise tolerance was measured as the distance achieved and breathlessness was assessed using visual analogue scales (VAS) which were scored before and after exercise and during recovery. RESULTS: No increase in mean walk distance after oxygen (288 v 283 m) and no improvement in mean breathlessness scores (58 v 54 mm) or recovery times occurred with oxygen taken either before (177 v 184 seconds) or after exercise (182 v 151 seconds). CONCLUSIONS: This group of patients with COPD derived no physiological or symptomatic benefit from oxygen breathed for short periods before or after submaximal exercise. Domiciliary oxygen should only be prescribed for such patients if they have shown objective evidence of benefit on exercise testing.


Related Articles

  • Long-Term Oxygen Therapy. Anthonisen, N. R. // Annals of Internal Medicine;Oct83, Vol. 99 Issue 4, p519 

    Examines the status of long-term outpatient oxygen therapy, particularly, as it is applied to patients with chronic obstructive pulmonary disease (COPD). Symptoms of COPD; Clinical benefits of oxygen therapy; Recommended predictor of the clinical course in patients with COPD; Other conditions...

  • Oxygen therapy in patients' homes. Sidebottom, Jo // Nursing Standard;7/1/2009, Vol. 23 Issue 43, p59 

    A nursing practice profile is presented that demonstrates the author's knowledge of oxygen therapy. The assessment of patients on long-term oxygen therapy is discussed. Peak expiratory flow measurement and spirometry tests are discussed. Treatment for patients with chronic obstructive pulmonary...

  • Oxygen.  // Reactions Weekly;5/21/2011, Issue 1352, p29 

    The article describes the case of an 86-year-old woman with chronic obstructive pulmonary disease (COPD) who developed respiratory failure during treatment with oxygen.


    An abstract of the article "Pendant Reservoir Cannula Offers Advantages Over Standard Cannu9la in a Model of COPD" by Sherry Babic and Robert L. Chatburn is presented.

  • Stable copd management in relation to the GOLD: Experience at a university hospital. Durán, Diana; Vargas, Olga Cecilia // Colombia Medica;oct-dic2008, Vol. 39 Issue 4, p337 

    Introduction: This paper presents a prospective and descriptive study discussing the outpatient care plan in a public hospital in Bogotá for patients with stable COPD according with the GOLD recommendations. The paper presents as well the influence of factors such as education,...

  • Homefill: better for your patient, better for your pocket? Murphie, Phyllis; Little, Stuart // Primary Care Respiratory Journal;Jun2011, Vol. 20 Issue 2, p223 

    The article discusses research which evaluates the Homefill II system using a postal survey in 20 patients with chronic obstructive pulmonary disease (COPD) who were using long term oxygen therapy (LTOT) in Great Britain. The system allows home refilling of ambulatory cylinders with integral...

  • Oxygen assessment and provision.  // Thorax;Dec2006 Supplement 2, Vol. 61, pii111 

    The article presents abstracts of medical research related to oxygen assessment and provision. They include "The Outcome of a Review of Oxygen Orders Following Patients' Attendance at an Oxygen Clinic," "Early Experience of a Physiotherapy led Ambulatory Oxygen Clinic," and "High Flow Oxygen as...

  • British Thoracic Society guidelines for home oxygen use in adults. Hardinge, Maxine; Annandale, Joe; Bourne, Simon; Cooper, Brendan; Evans, Angela; Freeman, Daryl; Green, Angela; Hippolyte, Sabrine; Knowles, Vikki; MacNee, William; McDonnell, Lynn; Pye, Kathy; Suntharalingam, Jay; Vora, Vandana; Wilkinson, Tom // Thorax;Jun2015 Supplement, Vol. 70, pi1 

    The British Thoracic Society (BTS) Home Oxygen Guideline provides detailed evidence-based guidance for the use of home oxygen for patients out of hospital. Although the majority of evidence comes from the use of oxygen in patients with chronic obstructive pulmonary disease, the scope of the...

  • Oxygen services overhaul. Praities, Nigel // Pulse;9/23/2009, Vol. 69 Issue 30, p4 

    The article reports on the move of the government of Great Britain to launch a restoration of home oxygen services. It notes that the move was made after the review of the current system showed that it was failing patients. It states that the review focuses on a particular concern with many...


Read the Article


Sign out of this library

Other Topics