TITLE

Chronic obstructive pulmonary disease • 10: Bullectomy, lung volume reduction surgery, and transplantation for patients with chronic obstructive pulmonary disease

AUTHOR(S)
Meyers, B.F.; Patterson, G.A.
PUB. DATE
July 2003
SOURCE
Thorax;Jul2003, Vol. 58 Issue 7, p634
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
There are currently three surgical treatments for emphysema: bullectomy, lung transplantation, and lung volume reduction surgery (LVRS). Unfortunately, most emphysema patients are poor candidates for any surgical intervention. A meticulous selection process is favoured in which indications and contraindications are considered and the best solution is devised for each patient. Patients with giant bullae filling half the thoracic volume and compressing relatively normal adjacent parenchyma are offered bullectomy; those with hyperinflation, heterogeneous distribution of destruction, forced expiratory volume in 1 second (FEV[sub 1]) > 20%, and a normal carbon dioxide tension (PCO[sub 2]) are offered LVRS; and patients with diffuse disease, lower FEV[sub 1], hypercapnia, and associated pulmonary hypertension are directed towards transplantation. Using these criteria, few patients are serious candidates for surgical procedures. Combinations of LVRS and lung transplantation, either simultaneously or sequentially, are possible but rarely necessary.
ACCESSION #
10595452

 

Related Articles

  • Long-term results of lung volume reduction surgery. Fujimoto, T.; Teschler, H.; Hillejan, L.; Zaboura, G.; Stamatis, G. // European Journal of Cardio-Thoracic Surgery;Mar2002, Vol. 21 Issue 3, p483 

    Objective: Lung volume reduction surgery (LVRS) is effective in the short and intermediate term for the improvement of pulmonary function and subjective symptoms in selected patients with advanced emphysema. The purpose of this study was to examine the long-term functional results of LVRS and to...

  • Smokers' Second Wind? Song, Sora // Time;6/2/2003, Vol. 161 Issue 22, p83 

    Discusses lung-volume reduction operations that are designed to decrease the capacity of the lungs in an attempt to improve their overall efficiency. Benefits of the surgery for people with emphysema; Results of a study by the National Institutes of Health; Effects of the surgery on people...

  • Mechanical Events In Physiopathology Of Idiopathic Pulmonary Emphysema: A Theoretical Analysis. Nazari, Stefano // Internet Journal of Pathology;2002, Vol. 2 Issue 2, p26 

    Lung volume reduction (LVR) surgery, now quite frequently used as a therapeutic option in lung emphysema, is aimed at advantageously interfering with the structural alterations of bronchoalveolar architecture and the thoracic cage and diaphragm changes characterizing the emphysema. All the...

  • Emphysema sufferers breathe easier. Miller, John D. // CMAJ: Canadian Medical Association Journal;11/02/99, Vol. 161 Issue 9, p1140 

    Reports on the use of lung-reduction surgery for people with emphysema. Advocation for the use of lung-volume-reduction surgery (LVRS); Benefits patients received following the procedure.

  • Lung Volume Reduction Surgery vs Medical Treatment: For Patients with Advanced Emphysema.  // Cardiopulmonary Physical Therapy Journal (American Physical Ther;Sep2005, Vol. 16 Issue 3, p24 

    Cites key research findings in 2005 comparing the efficacy of lung volume reduction surgery and medical treatment in patients with advanced emphysema. Therapeutic value of lung volume reduction surgery; Analysis of pertinent topics and relevant issues; Implications for studies of cardiopulmonary...

  • Emphysema: time to say farewell to therapeutic nihilism. Zoumot, Zaid; Jordan, Simon; Hopkinson, Nicholas S. // Thorax;Nov2014, Vol. 69 Issue 11, p973 

    The article focuses on the need to end the current trend of therapeutic nihilism in emphysema. Topics discussed include neglecting lung volume reduction surgery (LVRS) in the treatment of emphysema, increasing bronchoscopic approaches for lung volume reduction in emphysema and the development of...

  • Delay of airway epithelial wound repair in COPD is associated with airflow obstruction severity. Perotin, Jeanne-Marie; Adam, Damien; Vella-Boucaud, Juliette; Delepine, Gonzague; Sandu, Sebastian; Jonvel, Anne-Carole; Prevost, Alain; Berthiot, Gérard; Pison, Christophe; Lebargy, François; Birembaut, Philippe; Coraux, Christelle; Deslee, Gaëtan // Respiratory Research;2014, Vol. 15 Issue 11, p1 

    Background: Airway epithelium integrity is essential to maintain its role of mechanical and functional barrier. Recurrent epithelial injuries require a complex mechanism of repair to restore its integrity. In chronic obstructive pulmonary disease (COPD), an abnormal airway epithelial repair may...

  • Chronic obstructive pulmonary disease · 2: Pathology and biochemistry of emphysema. Hogg, J.C.; Senior, R.M. // Thorax;Sep2002, Vol. 57 Issue 9, p830 

    Part 2. Examines the pathology and biochemistry of emphysema. Cells responsible for the degradation of extracellular matrix in emphysema; Proteinase-antiproteinase hypothesis; Proteinases involved in alveolar septal destruction.

  • Influence of lung volume reduction surgery (LVRS) on health related quality of life in patients with chronic obstructive pulmonary disease. Goldstein, R.S.; Todd, T.R.J.; Guyatt, G.; Keshavjee, S.; Dolmage, T.E.; van Rooy, S.; Krip, B.; Maltais, F.; LeBlanc, P.; Pakhale, S.; Waddell, T.K. // Thorax;May2003, Vol. 58 Issue 5, p405 

    Background: The clinical value of LVRS has been questioned in the absence of trials comparing it with pulmonary rehabilitation, the prevailing standard of care in COPD. Patients with heterogeneous emphysema are more likely to benefit from volume reduction than those with homogeneous disease....

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics