TITLE

Epidemiology of tuberculosis on Gran Canaria: a 4 year population study using traditional and molecular approaches

AUTHOR(S)
Pena, M.J.; Caminero, J.A.; Campos-Herrero, M.I.; Rodríguez-Gallego, J.C.; García-Laorden, M.I.; Cabrera, P.; Torres, M.J.; Lafarga, B.; de Castro, F. Rodríguez; Samper, S.; Cañas, F.; Enarson, D.A.; Martin, C.
PUB. DATE
July 2003
SOURCE
Thorax;Jul2003, Vol. 58 Issue 7, p618
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: In recent years several population based studies using restriction fragment length polymorphism (RFLP) analysis have shown a higher rate of recent transmission of tuberculosis than previously thought. This study was undertaken to determine the transmission patterns of tuberculosis and the potential causes of recent transmission on the island of Gran Canaria (Spain). Methods: The strains of all patients diagnosed with tuberculosis confirmed by culture between 1 January 1993 and 31 December 1996 were typed by RFLP using the insertion sequence IS6110. A cluster was defined as two or more isolates with an identical RFLP pattern. Epidemiological linkage through contact tracing was investigated. Results: Of the total of 719 patients, 153 (21.3%) were excluded because there was inadequate bacterial DNA for genotyping (n = 129) or the isolates of Mycobacterium tuberculosis had less than five copies of IS6110 (n = 24). The isolates from 409 patients (72.3%) were grouped into 78 different clusters with an estimated 58.5% of the cases being due to recent transmission. Young age was the only significant predictor of clustering. Only in 147 (35.9%) of the 409 patients belonging to a cluster could an epidemiological link be found. 111 patients (19.6%) were identified as having had previous contact with a tuberculosis patient and 81 of them (72.9%) belonged to a cluster. The three largest clusters included 75, 49 and 20 patients, respectively. Conclusion: Recent transmission is frequent among patients with tuberculosis on Gran Canaria and could be associated with certain aspects of control measures. Some of the clusters described in the study could be due to the prevalence of particular strains of M tuberculosis on the island.
ACCESSION #
10595447

 

Related Articles

  • Lost world. MUIR, PETE // Cyclist;Apr2014, Issue 20, p64 

    A personal narrative is presented which explores the author's experience of visiting on a bicycle tour in Gran Canaria, Canary Islands.

  • WINTER WARMERS. Copestake, Andrew // Gay Times (09506101);Feb2004, Issue 305, p114 

    Describes Gran Canaria, Canary Islands located off the northwest coast of Africa, which serves as an ideal destination for gays during the winter season. Tourist attractions.

  • REVIEW Radisson Blu Resort, Gran Canaria.  // Conference & Incentive Travel;Sep2012, p59 

    A review is offered for Radisson Blu Resort located in Gran Canaria in Canary Islands. INSET: THE PRINGLES TEST.

  • HANNINEN TOPS IRC FIGHT. Lister, Graham // Motor Sport News: The Voice of British Motorsport;4/20/2011, p38 

    The article reports on the victory of racer Juho Hänninen at the Irish Rally Championship (IRC) in Gran Canaria, Canary Islands in April 2011.

  • GOING CHEAP. Davis, Gareth // Gay Times (09506101);Apr2004, Issue 307, p137 

    Features Playa del Inglés, a gay resort destination on Gran Canaria, Canary Islands. Services offered; Description of the Maspalomas gay beach; Menus offered at Los Almendros restaurant.

  • Spa time. Fletcher, Becky; Dunn, Marisa // Health & Fitness Magazine;May2015, p91 

    A review is offered for the Seaside Palm Beach Hotel and Spa located at the Seaside Palm Beach in the Gran Canaria island.

  • COME TOGETHER.  // BOYZ;12/3/2015, Issue 1265, p010 

    The article discusses the Together European Winter Festival held in Gran Canaria, Canary Islands on December 8, 2015.

  • GRAN CANARIA. Kyriazis, Stefan // Gay Times (09506101);Nov2012, Issue 412, p124 

    The article offers travel tips for Gran Canaria, Canary Islands, including recommendations to relax at the Seaside Palm Beach, engage in activities like helicopter riders and camel safaris and visit the Jardin de la Marquesa de Arucas botanical garden.

  • Learn to earn your Gran Canaria trip.  // Travel Trade Gazette UK & Ireland;8/8/2013, Issue 3061, p32 

    The article offers information related to travel destinations which include the prizes for the winners of the training course prize draw of the Gran Canaria, Canary Islands and quizzes regarding beaches and golf courses.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics