Asymptomatic Infection with Borrelia burgdorferi

Steere, Allen C.; Sikand, Vijay K.; Schoen, Robert T.; Nowakowski, John
August 2003
Clinical Infectious Diseases;8/15/2003, Vol. 37 Issue 4, p528
Academic Journal
The natural history of asymptomatic seroconversion to Borrelia burgdorferi has been unclear. We report here, on the basis of a post hoc assessment, the frequency and outcome of asymptomatic seroconversion to B. burgdorferi in participants of a large Lyme disease vaccine trial. We show that infection with B. burgdorferi may be asymptomatic but that asymptomatic infection is unusual in the United States.


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