Human Herpesvirus 8-- Associated Diseases in Solid-Organ Transplantation: Importance of Viral Transmission from the Donor

Luppi, Mario; Barozzi, Patrizia; Guaraldi, Giovannie; Ravazzini, Luisa; Rasini, Valeria; Spano, Carlotta; Riva, Giovanni; Vallerini, Daniela; Pinna, Antonio Daniele; Torelli, Giuseppe
August 2003
Clinical Infectious Diseases;8/15/2003, Vol. 37 Issue 4, p606
Academic Journal
Focuses on the transmission of human herpesvirus 8 (HHV-8) with grafts. Association of HHV-8 infection with the development of posttransplantation Kaposi sarcoma (KS) which affects renal and liver transplant recipients; Analysis of published cases of posttransplantation KS and associated disorders.


Related Articles

  • Reply to “KSHV reactivation in post-transplant Kaposi sarcoma”. Luppi, Mario; Barozzi, Patrizia; Facchetti, Fabio; Schulz, Thomas F.; Torelli, Giuseppe // Nature Medicine;Aug2003, Vol. 9 Issue 8, p986 

    Responds to a commentary made by C. Parravicini and colleagues' article on Kaposi sarcoma-associated herpesvirus (KSHV). Agreement with Parravicini that the majority of transplant Kaposi sarcoma cases may be the consequence of a reactivated viral infection; Role of the donor-derived virus in...

  • KSHV reactivation in post-transplant Kaposi sarcoma. Parravicini, Carlo; Scalamogna, Chiara; Calattini, Sara; Poli, Francesca; Scalamogna, Mario; Galli, Massimo; Moroni, Mauro; Corbellino, Mario // Nature Medicine;Aug2003, Vol. 9 Issue 8, p986 

    Comments on Patrizia Barozzi and colleagues' article on Kaposi sarcoma-associated herpesvirus (KSHV). Use of donor-derived, KSHV-specific T cells for the treatment of post-transplant Kaposi sarcoma; Incidence of post-transplant Kaposi sarcoma; Recommendations for baseline serologic testing for...

  • Seroprevalence of Human herpesvirus 8 (HHV-8) and incidence of Kaposi's sarcoma in Iran. Jalilvand, Somayeh; Shoja, Zabihollah; Mokhtari-Azad, Talat; Nategh, Rakhshandeh; Gharehbaghian, Ahmad // Infectious Agents & Cancer;2011, Vol. 6 Issue 1, p5 

    Seroepidemiological surveys show that the prevalence of human herpesvirus 8 (HHV-8) infection mostly varies in various geographical areas and reflects the local incidence of classic and endemic KS, being widespread in sub-Saharan Africa and Mediterranean countries and uncommon in the USA and...

  • Human Herpesvirus-8 and Kaposi Sarcoma After Kidney Transplantation Mechanisms of Tumor Genesis. Ahmadpoor, Pedram // Iranian Journal of Kidney Diseases;Jul2009, Vol. 3 Issue 3, p121 

    Human herpesviruses (HHVs) are able to escape from complete clearance by the immune system. Their ability to become latent is due to their delicate interferences with the immune system. This characteristic makes some of them known as important tumor viruses. Based on the prevalence of the...

  • Multifactorial etiology of Kaposi's sarcoma: a hypothesis. Haverkos, Harry W. // Journal of Biosciences;Dec2008, Vol. 33 Issue 5, p643 

    Kaposi's sarcoma (KS) is the most common cancer among AIDS patients in North America and Europe, and also occurs among elderly Mediterranean men, sub-Saharan African adults and children, and organ transplant recipients. In 1994 Chang et al identified a new herpes virus, HHV-8, as the cause of...

  • Tainted Donors. Rutledge, Barbara J. // Dermatology Times;Jun2003, Vol. 24 Issue 6, p24 

    Discusses the role of donor-derived progenitor cells in causing Kaposi's sarcoma. Techniques used in determining the origin of the kaposi's sarcoma cells; Effect of interleukin-12 on Kaposi's sarcoma; Clinical adverse effects of interleukin-12 therapy.

  • The Frequency of HHV-8 Infection in Otherwise Healthy Blood Donors as Well as Renal Allograft Recipients Living in Iran. Hosseini-Moghaddam, Seyed Mohammadmehdi; Keyvani, Hossein; Soleimanirahbar, Ata; Karimi, Gharib; Daneshvar, Simin; Basiri, Abbas; Razzaghi, Zahra; Nafar, Mohsen; Pour-Reza-Gholi, Fatemeh; Farhangi, Soudabeh // Archives of Iranian Medicine (AIM);Jul2013, Vol. 16 Issue 7, p376 

    Background: Different reports from Middle East countries demonstrated Kaposi's sarcoma (KS) in transplant population. This vascular malignancy occurs mostly among immunocompromised individuals. Human herpesvirus 8 (HHV-8) appears to be the causative factor for the development of this neoplasm....

  • Reply. Avery, Robin K. // Clinical Infectious Diseases;8/15/2003, Vol. 37 Issue 4, p607 

    Replies to comments on an article about the transmission of human herpesvirus 8 (HHV-8) infections with grafts by Luppi et al. Potential of the transmission of HHV-8 from the donor; Variety of syndromes that can be caused by HHV-8; Need for additional studies on whether periodic molecular...

  • Evidence Mounts That HHV8 Is Pivotal to Kaposi's Sarcoma Evolution. Bankhead, Charles // Dermatology Times;Aug97, Vol. 18 Issue 8, p30 

    Reports that human herpesvirus 8 (HHV8) plays a pivotal role in the etiology of Kaposi's sarcoma (KS). Other elements in favor of HHV8's role in the etiology of KS; How HHV8 was identified; One of the most promising approaches in controlling KS.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics