Acute Renal Failure Associated with Tenofovir Treatment in a Patient with Acquired Immunodeficiency Syndrome

Schaaf, B.; Aries, S.P.; Kramme, E.; Steinhoff, J.; Dalhoff, K.
August 2003
Clinical Infectious Diseases;8/1/2003, Vol. 37 Issue 3, pe41
Academic Journal
Reports on a case of acute renal failure due to proximal tubular necrosis associated with tenofovir treatment in a patient with AIDS. Role of tenofovir fumarate as a nucleotide reverse-transcriptase inhibitor licensed for treatment of HIV infection in patients for whom HIV treatment has failed; Suggestion that tenofovir might be toxic for proximal tubular cells.


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