Intravenous Immunoglobulin G Therapy in Streptococcal Toxic Shock Syndrome: A European Randomized, Double-Blind, Placebo-Controlled Trial

Darenberg, Jessica; Ihendyane, Nahla; Sjölin, Jan; Aufwerber, Ewa; Haidl, Sven; Follin, Per; Andersson, Jan; Norrby-Teglund, Anna
August 2003
Clinical Infectious Diseases;8/1/2003, Vol. 37 Issue 3, p333
Academic Journal
Evaluates the efficacy and safety of high-dose intravenous polyspecific immunoglobulin G (IVIG) as adjunctive therapy in streptococcal toxic shock syndrome (STSS). Mortality rate; Decrease in the sepsis-related organ failure assessment score in the IVIG group; Increase in plasma neutralizing activity against superantigens expressed by autologous isolates.


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