Mice, genes and men

May 1991
New Scientist;5/18/91, Vol. 130 Issue 1769, p9
Comments on `The Independent' newspaper's story on the discovery of a gene whose presence is essential for the development of a male mouse. Significance of the discovery on the field of science research in Great Britain; Major benefits of the gene's identity for medical researchers; Disadvantages of the gene discovery; Article writer's description of the gene discovery.


Related Articles

  • Complex traits: Mice line up for success. Muers, Mary // Nature Reviews Genetics;May2011, Vol. 12 Issue 5, p298 

    The article discusses the research on the genetic aspects of mouse recombinant inbred lines (RILs) that are being generated in the collaborative cross (CC), which references the study "Genetic analysis of complex traits in the emerging collaborative cross," by D. L. Aylor and colleagues in the...

  • Genetic hyping. Sapolsky, Robert M. // Sciences;Mar/Apr2000, Vol. 40 Issue 2, p12 

    Focuses on the study aimed at standardizing the various tests that have been devised to measure the effects of genes on mouse behaviors. Links between genetics and behavior; Chaos that resulted from the creation of a set of genetically indistinguishable mice; Explanations for the discrepancy in...

  • The mammalian gene function resource: the international knockout mouse consortium. Bradley, Allan; Anastassiadis, Konstantinos; Ayadi, Abdelkader; Battey, James; Bell, Cindy; Birling, Marie-Christine; Bottomley, Joanna; Brown, Steve; Bürger, Antje; Bult, Carol; Bushell, Wendy; Collins, Francis; Desaintes, Christian; Doe, Brendan; Economides, Aris; Eppig, Janan; Finnell, Richard; Fletcher, Colin; Fray, Martin; Frendewey, David // Mammalian Genome;Oct2012, Vol. 23 Issue 9/10, p580 

    In 2007, the International Knockout Mouse Consortium (IKMC) made the ambitious promise to generate mutations in virtually every protein-coding gene of the mouse genome in a concerted worldwide action. Now, 5 years later, the IKMC members have developed high-throughput gene trapping and, in...

  • On the Additive and Dominant Variance and Covariance of Individuals Within the Genomic Selection Scope. Vitezica, Zulma G.; Varona, Luis; Legarra, Andres // Genetics;Dec2013, Vol. 195 Issue 4, p1223 

    Genomic evaluation models can fit additive and dominant SNP effects. Under quantitative genetics theory, additive or "breeding" values of individuals are generated by substitution effects, which involve both "biological" additive and dominant effects of the markers. Dominance deviations include...

  • Using Genetically Engineered Mice for Radiation Research. Kirsch, David G. // Radiation Research;Sep2011, Vol. 176 Issue 3, p275 

    The laboratory mouse has been used for many decades as a model system for radiation research. Recent advances in genetic engineering now allow scientists to delete genes in specific cell types at different stages of development. The ability to manipulate genes in the mouse with spatial and...

  • Genome Patterns of Selection and Introgression of Haplotypes in Natural Populations of the House Mouse (Mus musculus). Staubach, Fabian; Lorenc, Anna; Messer, Philipp W.; Kun Tang; Petrov, Dmitri A.; Tautz, Diethard // PLoS Genetics;Aug2012, Vol. 8 Issue 8, Special section p1 

    General parameters of selection, such as the frequency and strength of positive selection in natural populations or the role of introgression, are still insufficiently understood. The house mouse (Mus musculus) is a particularly well-suited model system to approach such questions, since it has a...

  • Centralized mouse repositories. Donahue, Leah; Hrabe de Angelis, Martin; Hagn, Michael; Franklin, Craig; Lloyd, K.; Magnuson, Terry; McKerlie, Colin; Nakagata, Naomi; Obata, Yuichi; Read, Stuart; Wurst, Wolfgang; Hörlein, Andreas; Davisson, Muriel // Mammalian Genome;Oct2012, Vol. 23 Issue 9/10, p559 

    Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited. Ensuring...

  • Neuroscience: A technology for memory. Pastrana, Erika // Nature Methods;May2012, Vol. 9 Issue 5, p431 

    The article discusses several studies which investigate how brain of mammals stores and retrieves context-dependent memory. It says that studies have used transgenic mice to express the transcriptional activator tTA under the control of the promoter of the direct gene Fos. It states that the two...

  • New technologies for genetic manipulation of animal models: Forum introduction. Ziyi Li; Engelhardt, John F. // Reproductive Biology & Endocrinology;2003, Vol. 1, p78 

    The authors reflect on the increasing need for genetic animal models for bigger species to effectively address the pathophysiologic processes undergone by some human diseases. They claim that newer technologies must be developed to implement the required advancements in genetic modeling. He...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics