Celecoxib was as effective as diclofenac plus omeprazole in reducing recurrent ulcer bleeding in arthritis
- Controlled trials testing two or more treatments simultaneously. Doll, Richard // Journal of the Royal Society of Medicine;Oct2005, Vol. 98 Issue 10, p479
The article examines a simultaneous controlled trials testing of two or more treatments of gastric ulcers. It has found out that the use of a factorial design in controlled trials has a history of only seven decades. It has become established as a valuable technique that has enabled conclusions...
- Misoprostol prevents some NSAID-induced gastric ulcers. // Geriatrics;Sep95, Vol. 50 Issue 9, p57
Presents an abstract of the paper, `Misoprostol Coadministered With Diclofenac for Prevention of Gastroduodenal Ulcers: A One-Year Study,' by N.M. Agrawal et al, published in the journal, `Geriatrics,' dated September 1995.
- Polymeric Prodrugs of Diclofenac and in vivo Evaluation. Kemisetti, Durgaprasad; Manda, Sarangapani; Aukunuru, Jithan; Rapaka, Naga Kishore // International Journal of ChemTech Research;Aug-Sep2014, Vol. 6 Issue 5, p2637
The present study deals with the synthesis of prodrugs of diclofenac through an ester and amide linkage to PEG 1500 (polyethylene glycol) and PEG 6000. Diclofenac is most commonly and widely used OTC drug for analgesic and anti inflammatory activity. The prodrugs synthesized were characterized...
- ANTIULCER ACTIVITY OF AERIAL PARTS OF LUFFA ECHINATA ROXB. ETHANOLIC EXTRACT IN DICLOFENAC SODIUM INDUCED RATS. Kailasiya, Deepak; Jain, S. K.; Verma, Mohini; Deo Yadav, Rahul; Kanaujia, Vinod // Pharma Science Monitor;Jul2012, Vol. 3 Issue 3, p109
The present study was undertaken to determine the anti-ulcer potential of Luffa echinata Roxb, a standardized extract of Luffa echinata commonly known as Kakora. Effect of various doses (200.0 and 400.0 mg/kg,) of Luffa echinata was studied on gastric ulcers in pylorus ligation, Diclofenac...
- Aspirin + celecoxib easier to stomach than aspirin + naproxen. // Reactions Weekly;7/15/2006, Issue 1110, p1
This article presents the results of a randomized, double-blind, multicentre study which compares the impact of the administration of celecoxib plus aspirin with naproxen plus aspirin in lowering incidence of endoscopic gastric and duodenal ulcers. The incidence of endoscopic gastric and...
- Primary dressings for venous ulcers. Cornforth, Amber // Independent Nurse;6/1/2009, p31
The article discusses venous leg ulcers and the use of honey under compression as a primary dressing for venous ulcers. The author explores the possible healing mechanism of honey, the benefits of its use on wounds, and several studies that examined its use as a primary dressing under...
- Celecoxib vs. Standard NSAIDs in Patients with Arthritis. Zepf, Bill; Sadovsky, Richard // American Family Physician;3/15/2003, Vol. 67 Issue 6, p1372
Discusses the study 'Celecoxib Versus Diclofenac and Omeprazole in Reducing the Risk of Recurrent Ulcer Bleeding in Patients With Arthritis,' by F.K. Chan et al., from the December 26, 2002 issue of the 'New England Journal of Medicine.'
- CONDOR trial finds raised GI risk for diclofenac + omeprazole. // Reactions Weekly;6/26/2010, Issue 1307, p1
The article discusses a CONDOR trial about the impact of using combined diclofenac and omeprazole on gastrointestinal events. Findings suggested that the risk of GI events is four times higher in patients taking the drugs compared to those under celecoxib. It was found that the lower...
- A 'burning' question is how to fit DM into ulcer treatment programs. Mulligan, Margaret // Managed Healthcare;May99, Vol. 9 Issue 5, p32
Focuses on the incorporation of disease management into ulcer treatment programs in the United States. Development of protocols and disease-management programs; Etiology of ulcer.