Ezetimibe added to ongoing statin therapy reduced LDL cholesterol in primary hypercholesterolemia
- Ezetimibe for the treatment of primary (heterozygous-familial and non-familial) hypercholesterolaemia: NICE technology appraisal guidance. Charles, Z.; Pugh, E.; Barnett, D. // Heart;May2008, Vol. 94 Issue 5, p642
The article discusses the NICE technology appraisal guidance on ezetimibe for primary hypercholesterolaemia. The main points of the guidance include recommendation of ezetimibe monotherapy as an option for treatment for adults who are to be initiated on statin therapy, intolerant to statin...
- Statins reduce post-MI mortality. // Cortlandt Forum;10/25/2005, Vol. 18 Issue 10, p15
Reports on the study which found the potential of statins in reducing a myocardial infarction (MI) patient's chances of dying during hospitalization. Addition of clopidogrel would protect the worsening of MI conditions; Association of statins with lower incidence of cardiac arrest; Short- and...
- Statin monotherapy 'is best in atherosclerosis'. Baines, Emma // GP: General Practitioner;9/13/2004, p5
The article reports that, combining a statin with ezetimibe has no advantage over statins alone in treating patients with atherosclerosis, according to a review of existing research. Researchers looked at six studies comparing LDL reduction with a combination of a statin and ezetimibe versus a...
- Rosuvastatin: A Review of its Use in the Management of Dyslipidemia. Lesley J. Scott; Monique P. Curran; David P. Figgitt // American Journal of Cardiovascular Drugs;2004, Vol. 4 Issue 2, p117
Rosuvastatin (CrestorÂ®), an HMG-CoA reductase inhibitor (statin), has a favorable pharmacologic profile, including its selective uptake by hepatic cells, hydrophilic nature, and lack of metabolism by cytochrome P450 (CYP) 3A4 isoenzyme. This last property means that the potential for...
- Lowering cholesterol in patients with coronary artery disease â€“ the use of statins. Bukachi, F.; Rana, B. S.; Henein, M. Y. // Caribbean Health;Jul1999, Vol. 2 Issue 2, p14
The article reports on the use of statins in lowering cholesterol in patients with coronary artery diseases. Statins are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the enzyme whose action is the step in the cholesterol biosynthetic pathway. Correction of other risk factors...
- Placing PRINCE in Perspective. Simpson Jr., Ross J. // JAMA: Journal of the American Medical Association;7/4/2001, Vol. 286 Issue 1, p91
Editorial. Comments on a study in this issue by Albert and colleagues on the results of the Pravastatin Inflammation/CRP Evaluation (PRINCE) study. Discussion of the study's results; View that the study is based on good scientific rationale, and adds prospective data to evidence that statins...
- Statins may improve survival in HF. // Geriatrics;Nov2004, Vol. 59 Issue 11, p21
Reports on a study on the association of statin use and improved survival in patients with heart failure (HF) regardless of HF etiology. Definition of statin therapy; Comparison on the survival percentage rate of patients on statins with those not on statin; Effects of statins on one's health.
- Statin withdrawal in acute coronary syndromes. Heeschen, C.; Hamm, C. W.; Laufs, U.; DiLoreto, Stacy // Patient Care;Jun2002, Vol. 36 Issue 8, p84
Discusses research being done on statin withdrawal in acute coronary syndromes. Reference to a study by C. W. Hamm et al, published in a 2002 issue of "Circulation"; Risk of patients with acute coronary syndromes who are pretreated with statin therapy; Patients assessed by the researchers.
- Patients fail to take statins correctly. Pedder, Cato // Pulse;1/19/2004, Vol. 64 Issue 3, p7
Reports on the re-emergence of statins in medical research in Great Britain. Research on compliance, combined therapy and pharmacy-based cholesterol screening; Percentage of failures committed by patients in taking statins correctly; Importance of taking statins regularly.