Opportunities and Options for Treatment Research in Resource-Constrained Settings

Volberding, Paul A.
July 2003
Clinical Infectious Diseases;7/1/2003 Supplement 1, Vol. 37, pS1
Academic Journal
HIV clinical research faces limitations even in research-rich settings. Even though important questions remain unanswered, clinical trials will probably never be conducted that address, prospectively, when treatment is optimally indicated, for example. In resource-constrained settings, large, prospective clinical trials are also unlikely. On the other hand, ones with a more observational design or that compare cohort experiences may well be feasible and able to provide information important in those settings, as well as in regions with abundant financial resources.


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