Differences in the effectiveness of serum biomarkers for the diagnosis of bacterial infections in adult and elderly patients admitted to the emergency department

YILMAZ, Hava; DURAN, Latif; YANIK, Keramettin; ALTUNTAS, Mehmet; SÜNBÜL, Mustafa
June 2015
Turkish Journal of Medical Sciences;2015, Vol. 45 Issue 3, p553
Academic Journal
Background/aim: This study aimed to evaluate the superiority of procalcitonin (PCT), C-reactive protein (CRP) levels, white blood cell (WBC) counts, and erythrocyte sedimentation rate (ESR) in discriminating among infection, systemic inflammatory response syndrome (SIRS), and sepsis, and their differences according to age groups. Materials and methods: The patients were divided into an adult group and a geriatric group (over 65 years) and classified according to the presence of infection, SIRS, and sepsis. The patients' laboratory values (PCT, CRP, WBC, ESR), demographic characteristics, and vital signs were taken into consideration. Results: When the laboratory parameters were evaluated, there were no significant differences in the PCT, WBC, and ESR values between the age groups (P > 0.05). CRP was significantly higher in the adult patient group compared to the geriatric group (P < 0.001). When the two groups were compared in terms of infection, there were no significant differences in the PCT levels and the WBC count (P > 0.05) in SIRS and sepsis. In addition, the CRP levels and the ESR were significantly higher in the adult sepsis patients when compared with the geriatric patients (P < 0.001). Conclusion: PCT levels do not distinguish among infection, SIRS, and sepsis in adult and geriatric age groups.


Related Articles

  • Increased serum levels of ischemia-modified albumin and C-reactive protein in type 1 diabetes patients with ketoacidosis. Ma, Shao-gang; Jin, Yue; Xu, Wei; Hu, Wen; Bai, Feng; Wu, Xiao-juan // Endocrine (1355008X);Dec2012, Vol. 42 Issue 3, p570 

    Ischemia-modified albumin (IMA) levels have been advocated as a biomarker for evaluating the oxidative stress status. No data are showed on the potential role of IMA in type 1 diabetes (T1D). We aimed to establish the correlation among serum levels of IMA, C-reactive protein (CRP), and diabetic...

  • The Clinical Value of Serum Tau Protein in Sepsis-Associated Encephalopathy. TÜREDİ, Süleyman; DAŞDİBİ, Bengü; TÜRKMEN, Süha; KARACA, Yunus; TATLI, Özgür; MENTEŞE, Ahmet; YILMAZ, Gürdal; GÜNDÜZ, Abdulkadir // Turkish Journal of Emergency Medicine;2013, Vol. 13 Issue 2, p69 

    Objectives Sepsis-associated encephalopathy (SAE) is the most widespread metabolic encephalopathy, which continues to be clinically evaluated with the Glasgow Coma Scale (GCS). This study aimed to determine the clinical utility of serum tau protein as an effective and easily attainable...

  • The National Capitol Region's Emergency Department Syndromic Surveillance System: Do Chief Complaint and Diagnosis Yield Different Results? Begier, Elizabeth M.; Sockwell, Denise; Branch, Leslie M.; Davies-Cole, John O.; Jones, LaVerne H.; Edwards, Leslie; Casani, Julie A.; Blythe, David // Emerging Infectious Diseases;Mar2003, Vol. 9 Issue 3, p393 

    Presents a study which compared syndromic categorization of chief complaint and discharge diagnosis for emergency department visits to two hospitals in the U.S. National Capitol Region. Methods; Results; Discussion.

  • A Model for Forecasting Emergency Hospital Admissions: Effect of Environmental Variables. Díaz, J.; Alberdi, J.C.; Pajares, M.S.; Pharm, L.; López, C.; López, R.; Lage, M.B.; Otero, A. // Journal of Environmental Health;Oct2001, Vol. 64 Issue 3, p9 

    Presents model patterns and trends in emergency hospital admissions at Gregorio Maranon University Teaching Hospital in Madrid, Spain. Associations between admissions and number of environmental variables; Causes of emergency disease admissions; Factors affecting the emergency admissions.

  • More RNs, Fewer Readmissions.  // Trustee;Jun2011, Vol. 64 Issue 6, p3 

    The article discusses a Robert Wood Johnson Foundation-funded study which found that the chances of patient readmission in hospitals are lower when registered nurse nonovertime staffing in emergency departments is higher.

  • Reducing returns: Hospitals target costly readmissions, ER patient flow. GREENE, JAY // Crain's Detroit Business;1/10/2011, Vol. 27 Issue 2, p11 

    The article discusses a study undertaken to reduce unnecessary hospital readmissions and improve patient flow in the emergency department in Michigan.

  • Frequent attenders at emergency departments: a linked-data population study of adult patients. Jelinek, George A.; Jiwa, Moyez; Gibson, Nicholas P.; Lynch, Ann-Maree // Medical Journal of Australia;11/17/2008, Vol. 189 Issue 10, p552 

    The article discusses a study which examined the characteristics of adult patient attendances to emergency departments (EDs) in Perth, Western Australia hospitals by patients' frequency of attendance. Results showed a mean of 1.5 attendances per individual per year. In addition, most patients...

  • Do emergency tests help in the management of acute medical admissions? Sandler, Gerald // British Medical Journal (Clinical Research Edition);10/13/1984, Vol. 289 Issue 6450, p973 

    Evaluates the usability of emergency tests in the management of acute medical admissions in Great Britain. Assessment on the usefulness of several diagnostic tests; Reasons for the use of emergency tests by house officers; Abolition of routine investigation procedures.

  • Admissions schemes 'backfire'. Anekwe, Lilian // Pulse;3/23/2011, Vol. 71 Issue 11, p4 

    The article presents the findings of a study conducted by Nuffield Trust and funded by the Great Britain Department of Health which revealed the possibility of general practitioners (GPs) to struggle to achieve reductions in emergency admissions under new quality of framework (QOF) targets set...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics