TITLE

Epidemiology and clinical manifestations of juvenile myoclonic epilepsy (JME) in Iran

AUTHOR(S)
Asadi-Pooya, Ali; Hashemzehi, Zabihollah; Emami, Mehrdad
PUB. DATE
May 2015
SOURCE
Neurological Sciences;May2015, Vol. 36 Issue 5, p713
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Because most descriptive studies did not specifically analyze the syndromes of idiopathic generalized epilepsy (IGE), including juvenile myoclonic epilepsy (JME), epidemiologic data concerning these syndromes are scarce or often unreliable. In this retrospective chart review study, all patients with a clinical diagnosis of JME were recruited at the outpatient epilepsy clinic at Shiraz University of Medical Sciences, from 2008 to 2013. Demographic variables and relevant clinical and EEG variables were summarized descriptively. 2,750 patients with epilepsy were registered at our epilepsy clinic; 239 patients (8.7 %) were diagnosed as having JME. Female to male ratio was 1.7. Age at seizure onset was 15 ± 3.5 years. Generalized tonic-clonic seizures were reported by 225 patients (94.1 %) and absences by 90 (37.6 %). Electroencephalography (EEG) was abnormal in 69.6 % of the patients. JME is one of the most common syndromes of IGEs. The key element in making the correct diagnosis is obtaining a detailed clinical history. MRI or laboratory tests in a patient, in whom you are suspecting JME are not necessary. Even EEG has some limitations and normal or even atypical findings in a patient with typical history for JME should not deter from the correct diagnosis.
ACCESSION #
102426720

 

Related Articles

  • Clinical Development of Antiepileptic Drugs for Children Garofalo, Elizabeth // Neurotherapeutics;Jan2007, Vol. 4 Issue 1, p70 

    Summary: A clinical development plan specific to children is a necessary component of every development plan for a new antiepileptic drug (AED). In the last decade, considerable discussion has occurred in the medical and regulatory communities, resulting in specific pediatric drug development...

  • Brain Waves, Seizures and the Child with Autism. Tuchman, Roberto // Exceptional Parent;Mar2003, Vol. 33 Issue 3, p104 

    Discusses the association of seizures and epilepsy with autism in children. Frequency of seizures and abnormal brain waves in autism; Measurement of the brain waves using electroencephalogram; Percentage of autistic children with epilepsy.

  • Prospective Study of 2 Bed Alarms for Detection of Nocturnal Seizures. Fulton, Stephen; Poppel, Kate Van; McGregor, Amy; Ellis, Michelle; Patters, Andrea; Wheless, James // Journal of Child Neurology;Nov2013, Vol. 28 Issue 11, p1430 

    For parents of children with epilepsy, seizures occurring in sleep are a major concern. Risk factors for sudden unexplained death in epilepsy patients include being in bed and generalized tonic-clonic seizures. A device for detecting nocturnal seizure activity would be valuable. Children with...

  • Hot-water epilepsy: a new Caucasian case. De Keyzer, Kristel; Corthouts, Ivo; Van Coster, Rudy; Verhelst, Helene // European Journal of Pediatrics;Mar2005, Vol. 164 Issue 3, p184 

    Presents a study on hot-water epilepsy. Symptoms of hot-water epilepsy; Prevalence of hot-water epilepsy in infants and children; Methods to control seizures of people with hot-water epilepsy; Treatment for hot-water epilepsy.

  • Parametric and Nonparametric EEG Analysis for the Evaluation of EEG Activity in Young Children with Controlled Epilepsy. Sakkalis, Vangelis; Cassar, Tracey; Zervakis, Michalis; Camilleri, Kenneth P.; Fabri, Simon G.; Bigan, Cristin; Karakonstantaki, Eleni; Micheloyannis, Sifis // Computational Intelligence & Neuroscience;2008, Special section p1 

    There is an important evidence of differences in the EEG frequency spectrum of control subjects as compared to epileptic subjects. In particular, the study of children presents difficulties due to the early stages of brain development and the various forms of epilepsy indications. In this study,...

  • A Suggested Approach to the Etiologic Evaluation of Status Epilepticus in Children: What to Seek After the Usual Causes Have Been Ruled Out. Watemberg, Nathan; Segal, Gil // Journal of Child Neurology;Feb2010, Vol. 25 Issue 2, p203 

    Status epilepticus represents a true neurologic emergency that requires immediate treatment to stop seizure activity and prompt diagnostic evaluation to recognize potentially treatable causes. Although an etiology may be detected in many cases, in a significant number of patients the cause is...

  • EEG -- Infantile Spasms. McGlannan, Frances; Watanabe, Kazuyoshi; Iwase, Katsuhiko; Hara, Kimiko // Journal of Learning Disabilities;Apr1974, Vol. 7 Issue 4, p212 

    This article reports on a study which described the developmental course of infantile spasms and hypsarrhythmia. It has been generally accepted that infantile spasms are not a disease entity, but are an age-specific response of the infant brain, and that the characteristic...

  • Early Myoclonic Encephalopathy. KAMATE, MAHESH; MAHANTSHETTI, NIRANJANA; CHETAL, VIVEK // Indian Pediatrics;Sep2009, Vol. 46 Issue 9, p804 

    Early myoclonic encephalopathy (EME) is a rare malignant epileptic syndrome. The erratic myoclonus with or without focal motor seizures, onset before 3 months of age, and persistent suppression-burst pattern in electroencephalograph (EEG) are accepted as the diagnostic criteria for EME. We...

  • Metabolic Evaluation of Infantile Epilepsy: Summary Recommedations of the Amilfi Group. Buist, Neil R.M.; Dulac, Olivier; Bottiglieri, Teodoro; Gärtner, Jutta; Rinaldo, Piero; Wolf, Nicole I. // Journal of Child Neurology;Dec2002 Supplement 3, Vol. 17, p3S98 

    Discusses disciplines of clinical neurology and metabolic investigation and provide information about specific metabolic disorders associated with infantile epilepsy. Significance of electroencephalography in the diagnosis of newborns and infants with seizures; List of specialized assays and...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics