TITLE

Hypercalcemia and distal renal tubular acidosis: an association not only in the newborn

AUTHOR(S)
Pela, Ivana; Seracini, Daniela; Lavoratti, Giancarlo; Materassi, Marco
PUB. DATE
August 2003
SOURCE
Pediatric Nephrology;Aug2003, Vol. 18 Issue 8, p850
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Distal renal tubular acidosis is a possible etiology of hypercalcemia in newborn children. Hypercalcemia in newborn infants with distal renal tubular acidosis is probably due to calcium overload secondary to acidosis-induced bone dissolution and to incomplete excretion of the endogenous calcium load because of the reduced glomerular function characteristic of the newborn period. Severe dehydration increases the calcium reabsorption by the proximal tubule as occurs during diuretic therapy with thiazide derivatives.
ACCESSION #
10227331

 

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