TITLE

A Qualitative and Quantitative Analysis of AgNORs in Keratocystic Odontogenic Tumor, Unicystic Ameloblastoma and Multicystic Ameloblastoma

AUTHOR(S)
ANANTHANENI, ANURADHA; UDAYASHANKAR, URMILA; GUDURU, VIJAY SRINIVAS; PRASAD, V. V. S. RAM; DEVI RAMISETTY, SABITHA; NAMALA, SRILEKHA; BADAVATH, KIRAN KUMAR NAIK
PUB. DATE
September 2014
SOURCE
Journal of Clinical & Diagnostic Research;Sep2014, Vol. 8 Issue 9, p14
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Aims: A comparative evaluation of proliferation activity in unicystic ameloblastoma (UA), multicystic ameloblastoma (MA) and keratocystic odontogenic tumor (KCOT) using silver staining technique. Settings and Design: In the present study 21 histopathologically confirmed paraffin blocks,7 each of UA, MA and KCOT were selected and stained with silver nitrate. Materials and Methods: For quantitative analysis, 100 cells were counted at 10OOx magnification for AgNORs and the mean value was calculated. Qualitative analysis of AgNORs included normal (oval shaped) and abnormal groups (bean shaped) in the lesion. Statistical Analysis: The statistical analysis of data was done by a specialist statistician using two way ANOVA and multiple comparisons with Tukey's test in advanced excel. Results: The AgNOR count was more in KCOT when compared to MA and UA with the pattern of distribution of AgNORs more in basal than in the parabasal layer in KCOT. The qualitative analysis showed small to large oval AgNOR's in KCOT and few clusters in MA whereas in UA irregular clusters were seen. Conclusion: This concludes the expediency of AgNOR staining in reflecting the high proliferation rate and a more aggressive behavior of KCOT in comparison to MA and UA which signifies requirement of a more hostile surgical approach in KCOT to avoid recurrences following different treatment modalities.
ACCESSION #
101630548

 

Related Articles

  • "Dredging Method"- A Conservative Surgical Approach for the Treatment of Ameloblastoma of Jaw. Sadat, S. M. A.; Ahmed, M. // Journal of Bangladesh College of Physicians & Surgeons;May2011, Vol. 29 Issue 2, p72 

    Ameloblastoma is an aggressive benign odontogenic tumor of jaws with different clinical features and histologic patterns. The resection of mandible in growing young patient is associated with number of complications such as loss of jaw bone support, deformity, dysfunction and psychological...

  • Ameloloblastic carcinoma - a case report. Markose, Eldho; Mani, Varghese // International Journal of Dental Clinics;2010, Vol. 2 Issue 4, p54 

    The ameloblastoma is the prototype of a benign neoplasm with odontogenic origin. It will exhibit cell replication and growth throughout its existence, but it will not metastasize. The rare cases of amelobastoma that have metastasized are termed malignant ameloblastoma. Alternatively ameloblastic...

  • Plexiform Ameloblastoma. Celur, Sreelalita; Babu, K. Sunil // International Journal of Clinical Pediatric Dentistry;Jan-Apr2012, Vol. 5 Issue 5, p78 

    The ameloblastoma is a benign but aggressive neoplasm of odontogenic origin. However, no enamel or hard tissue is formed by the tumor cells. Ameloblastomas are infamous for their invasive growth and their tendency to recur. Robinson (1937) as a benign tumor that is 'usually unicentric,...

  • Metastasizing granular cell ameloblastoma. Bansal, Anju; Bhatnagar, Amar; Saxena, Sunita // Journal of Oral & Maxillofacial Pathology (0973029X);Jan2012, Vol. 16 Issue 1, p122 

    Ameloblastoma is a slow growing odontogenic epithelial tumor of jaw. It accounts for 1% of all tumors and cysts arising in maxilla and mandible. Although it is locally invasive and has a marked tendency to recur, metastasis is rare. Of the various histological patterns of ameloblastoma, the...

  • Odontoameloblastoma: A case report. Negi, Amita; Puri, Abhiney; Nangia, Rajat; Sachdeva, Alisha // Journal of Oral & Maxillofacial Pathology (0973029X);May-Aug2015, Vol. 19 Issue 2, p251 

    Odontoameloblastoma (OA) is an extremely rare odontogenic tumor that contains an ameloblastomatous component together with odontoma-like elements. Till date, very few cases have fulfilled the criteria of the current World Health Organization classification of odontogenic tumors. It is...

  • A rare case of hybrid odontogenic tumor: Calcifying epithelial odontogenic tumor combined with ameloblastoma. Wadhwan, Vijay; Sharma, Preeti; Bansal, Vishal // Journal of Oral & Maxillofacial Pathology (0973029X);May-Aug2015, Vol. 19 Issue 2, p290 

    A hybrid odontogenic tumor comprising two distinct lesions is extremely rare. Nevertheless, such tumors have been reported in the literature for academic and research interest. However, it is still obscure whether they behave as a new entity or they solely present separate histopathologic...

  • Unicystic Ameloblastoma in a Young Female: A Case Report and Review of Literature. Kanneppady, Sham Kishor; Sakri, Santosh B.; Nanditha, S.; Chatra, Laxmikanth; Prashanth Shenoy, K. // World Journal of Dentistry;Jul2011, Vol. 2 Issue 3, p263 

    Ameloblastoma is an archetype of a true neoplasm of odontogenic origin. Most ameloblastomas have been classically described as a multilocular cyst-like lesion of the jaw. The unicystic variant is far less frequent and has been reported in only 6% of ameloblastomas. The presented patient is an...

  • Adenomatoid Odontogenic Tumour: Review and Case Report. Batra, Puneet; Prasad, Shyam; Parkash, Hari // Journal of the Canadian Dental Association;Apr2005, Vol. 71 Issue 4, p250 

    Adenomatoid odontogenic tumour is a benign (hamartomatous), noninvasive lesion with slow but progressive growth. The 3 variants -- follicular, extrafollicular and peripheral -- present with identical histological findings. This report describes a patient with a large adenomatoid odontogenic...

  • Compound Odontoma Associated With Maxillary Impacted Permanent Central Incisor Tooth: A Case Report. Dagistan, Saadettin; Goregen, Mustafa; Miloglu, Ízkan // Internet Journal of Dental Science;2008, Vol. 5 Issue 2, p1 

    Odontomas, the most often seen ones among odontogenic tumors, are usually asemptomatic and discovered in routine radiographic examinations. Althoug odontomas are generally included in the calcified odontogenic tumors, most authorities will concede that these lesions are more properly considered...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics