TITLE

Repeated antenatal intracranial haemorrhage: magnetic resonance imaging in a fetus with alloimmune thrombocytopenia

AUTHOR(S)
Hidebrandt, T.; Powell, T.
PUB. DATE
November 2002
SOURCE
Archives of Disease in Childhood -- Fetal & Neonatal Edition;Nov2002, Vol. 87 Issue 3, p222
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Neonatal alloimmune thrombocytopenia is caused by transplacental passage of maternal platelet specific antibodies leading to destruction of fetal platelets. Published estimations of incidence range from 1.5 per 1000 neonates to 1 per 5000 neonates. Most intracranial haemorrhages occur in the third trimester, but early cases have been reported, possibly recurrent. The most common site of intracranial haemorrhage is beneath the cerebral cortex, with possible expansion to a subarachnoid bleed and dissection through the brain reaching the ventricles, resulting in the appearance of schizencephaly.
ACCESSION #
10082755

 

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