The Use of Economic Modeling to Determine the Hospital Costs Associated with Nosocomial Infections

Roberts, Rebecca R.; Scott II, R. Douglas; Cordell, Ralph; Solomon, Steven L.; Steele, Lynn; Kampe, Linda M.; Trick, William E.; Weinstein, Robert A.
June 2003
Clinical Infectious Diseases;6/1/2003, Vol. 36 Issue 11, p1424
Academic Journal
Hospital-associated infection is well recognized as a patient safety concern requiring preventive interventions. However, hospitals are closely monitoring expenditures and need accurate estimates of potential cost savings from such prevention programs. We used a retrospective cohort design and economic modeling to determine the excess cost from the hospital perspective for hospital-associated infection in a random sample of adult medical patients. Study patients were classified as being not infected (n = 139), having suspected infection (n = 8), or having confirmed infection (n = 17). Severity of illness and intensive unit care use were both independently associated with increased cost. After controlling for these confounding effects, we found an excess cost of $6767 for suspected infection and $15,275 for confirmed hospital-acquired infection. The economic model explained 56% of the total variability in cost among patients. Hospitals can use these data when evaluating potential cost savings from effective infection-control measures.


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