Familial diagnostic experiences in paediatric oncology

Evans, N T; Wakefield, C E; McLoone, J K; Cohn, R J
January 2015
British Journal of Cancer;1/6/2015, Vol. 112 Issue 1, p20
Academic Journal
Background:Diagnostic delays may not have significant prognostic implications in paediatric oncology, but psychological impacts remain understudied.Methods:Interviews exploring diagnostic experiences were conducted with childhood cancer survivors (n=19), parents (n=78) and siblings (n=15).Results:Median diagnostic time was 3 weeks. Participants described a mixture of rapid diagnoses (28.9%), plus delayed appraisal intervals (that is, parent- or patient-associated diagnostic delays; 40.0%) and diagnostic intervals (that is, healthcare-associated delays; 46.7%). Families experiencing delays described guilt and anger and deleterious impacts on the family-clinician relationship. Some believed delays impacted on treatment and prognosis.Conclusions:The effect of the diagnostic experience can be considerable.


Related Articles

  • SOLIDNI TUMORI U DECE. JANIĆ, Dragana // Pedijatrija Danas: Pediatrics Today;2009, Vol. 5 Issue 1, p43 

    The treatment of children with malignant disease has, in recent decades, seen an immense improvement, with more than two thirds of children now being cured. Nevertheless, clinicians and researchers are still confronted with the task of devising new strategies for treating diseases that continue...

  • MicroRNAs in clinical oncology: at the crossroads between promises and problems. Metias, S. M.; Lianidou, E.; Yousef, G. M. // Journal of Clinical Pathology;Sep2009, Vol. 62 Issue 9, p6 

    MicroRNAs (miRNAs) are small RNAs that do not code for proteins, but function by controlling protein expression of other genes. miRNAs have been shown to control cell growth, differentiation and apoptosis. Shortly after their discovery, miRNAs have been found to be associated with cancer....

  • Receiver operating characteristic (ROC) to determine cut-off points of biomarkers in lung cancer patients. Weiss, Heidi L.; Niwas, Santosh; Grizzle, William E.; Piyathilaked, Chandrika // Disease Markers;2003/2004, Vol. 19 Issue 6, p273 

    The role of biomarkers in disease prognosis continues to be an important investigation in many cancer studies. In order for these biomarkers to have practical application in clinical decision making regarding patient treatment and follow-up, it is common to dichotomize patients into those with...

  • Cancer: 25 years of progress. Selwood, Karen // Paediatric Nursing;May2009, Vol. 21 Issue 4, p3 

    The author reflects on progress which has been made in the treatment of pediatric oncology in Great Britain since 1984. She suggests that pediatric oncology has changed radically in the past 25 years, with new approaches to diagnosis and treatment, clinical trials, advances in surgery,...

  • Surgical intervention strategies for pediatric ovarian tumors: experience with 60 cases at one institution. Tajiri, Tatsuro; Souzaki, Ryota; Kinoshita, Yoshiaki; Yosue, Ryota; Kohashi, Kenichi; Oda, Yoshinao; Taguchi, Tomoaki // Pediatric Surgery International;Jan2012, Vol. 28 Issue 1, p27 

    Purpose: The aim of this study was to assess the surgical intervention strategies for pediatric ovarian tumors. Methods: The clinical features and treatment were analyzed for 60 children with ovarian tumors treated at our institution between 2000 and 2010. Results: Twenty-one of the 60 patients...

  • Current therapeutic strategies for childhood hepatic tumors: surgical and interventional treatments for hepatoblastoma. Hishiki, Tomoro // International Journal of Clinical Oncology;Dec2013, Vol. 18 Issue 6, p962 

    Surgery is the mainstay of multimodal treatment for hepatoblastomas. Among the various staging systems used, PRETEXT is currently adopted in all major study groups worldwide as a common pretreatment staging system. Although variations of treatment strategies among study groups exist, the...

  • Dilemma for Pediatricians in Detecting Retinoblastoma. Nelson, Leonard B. // Journal of Pediatric Ophthalmology & Strabismus;May/Jun2004, Vol. 41 Issue 3, p142 

    Focuses on retinoblastoma in children. Role of leukocoria in the diagnosis of retinoblastoma; Difficulty of diagnosing the disease in its early stage; Impact on the functional vision of the patient.

  • Pediatric papillary thyroid carcinoma: outcomes and survival predictors in 2504 surgical patients. Golpanian, Samuel; Perez, Eduardo; Tashiro, Jun; Lew, John; Sola, Juan; Hogan, Anthony; Perez, Eduardo A; Lew, John I; Sola, Juan E; Hogan, Anthony R // Pediatric Surgery International;Mar2016, Vol. 32 Issue 3, p201 

    Objective: To evaluate outcomes and predictors of survival of pediatric thyroid carcinoma, specifically papillary thyroid carcinoma.Methods: SEER was searched for surgical pediatric cases (≤20 years old) of papillary thyroid carcinoma diagnosed between 1973 and...

  • Current therapeutic strategies for childhood hepatic malignant tumors. Hiyama, Eiso // International Journal of Clinical Oncology;Dec2013, Vol. 18 Issue 6, p943 

    The two main malignant hepatic tumors in children are hepatoblastomas (HBLs) and hepatocellular carcinomas (HCCs). The past two decades have brought significant improvement to the outcomes of children diagnosed with malignant hepatic tumors, especially HBL, due to improvements in diagnosis and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics