Vancomycin-Intermediate Staphylococcus aureus with Phenotypic Susceptibility to Methicillin in a Patient with Recurrent Bacteremia

Naimi, Timothy S.; Anderson, Daniel; O'Boyle, Carol; Boxrud, David J.; Johnson, Susan J.; Tenover, Fred C.; Lynfield, Ruth
June 2003
Clinical Infectious Diseases;6/15/2003, Vol. 36 Issue 12, p1609
Academic Journal
Vancomycin-intermediate Staphylococcus aureus (VISA) are an emerging problem. We observed a statistically significant inverse relationship in the MICs of vancomycin and oxacillin in S. aureus isolates from a patient undergoing hemodialysis who received 26 weeks of treatment with vancomycin during November 1999 through April 2000. All isolates were mecA positive and were indistinguishable by pulsed-field gel electrophoresis. The evolving susceptibility patterns of this strain highlight the challenges of detecting and treating VISA infections.


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