TITLE

Antimicrobial Susceptibilities and Clinical Characterization of Pseudomonas aeruginosa Isolates from Urinary Tract Infections

AUTHOR(S)
Zhang, Xiaobing; Niu, Siqiang; Zhang, Liping
PUB. DATE
December 2014
SOURCE
Urologia Internationalis;Dec2014, Vol. 93 Issue 4, p464
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Introduction:Pseudomonas aeruginosa is a uropathogen that is mainly involved in nosocomial infection. The aim of this study was to analyze the antimicrobial susceptibilities and clinical characterization of P. aeruginosa isolates from urinary tract infections (UTIs). Materials and Methods: The study collected all P. aeruginosa UTI strains from a hospital in Chongqing, China, from January 1st, 2010 to December 31st, 2011. The antibiotic susceptibilities of the P. aeruginosa isolates were analyzed using the agar dilution method and the genotypes were assessed using random amplification of polymorphic DNA-PCR (RAPD-PCR). The clinical characteristics of the patients with UTIs were collected from the hospital information systems, and significance was analyzed using the proportion test. Results: A total of 2,778 episodes of culture-proven UTIs were used in the study. There were 198 infections (7.1%) caused by P. aeruginosa. P. aeruginosa strains were highly resistant to most drugs tested. The RAPD-PCR data revealed that the 198 P. aeruginosa infections had 82 different genotypes. Antibacterial use, previous UTI, urinary tract catheter and urinary tract operation were found to be risk factors for the development of UTIs. Conclusions:P. aeruginosa is the second most common UTI pathogen in our hospital. We should closely monitor patients with risk factors for P. aeruginosa infection. © 2014 S. Karger AG, Basel
ACCESSION #
100138561

 

Related Articles

  • Identification of Beta-Lactamase-Producing Pseudomonas aeruginosa with Multiple Antibiotic Resistances. Fazzeli, Hossein; Faghri, Jamshid; Kabiri, Payam; Fatahibafghi, Mehdi; Arabestani, Mohammad Reza // Journal of Isfahan Medical School;11/14/2011, Vol. 29 Issue 154, p1 

    Background: The clinical use of antibiotics in treatment of Pseudomonas aeruginosa infections causes resistant to multiple drugs increasingly. P. aeruginosa could produce beta lactamase enzyme to beta lactam antibiotics that causes many problems. The purpose of this study is analysis of the...

  • Correlation between antibiotic resistance and virulence of Pseudomonas aeruginosa clinical isolates. SONBOL, Fatma Ibrahim; El Fattah KHALIL, Maha Abd; MOHAMED, Abdelfattah Badr; ALI, Sameh Samir // Turkish Journal of Medical Sciences;2015, Vol. 45 Issue 3, p568 

    Background/aim: Virulent Pseudomonas aeruginosa is frequently life-threatening and often challenging to treat, and the emergence of multidrug-resistant isolates presents a critical problem for patients. The aim of the study was concerned with molecular analysis of the virulence factors and...

  • Study of Causative Bacterial Agents of Urinary Tract Infections and Determining Their Antibiotic Susceptibility Pattern in Clients of Tabriz's Clinics. Aghdam, Vahid Badiheh; Anzabi, Younes; Hassanzadeh, Mousa; Anvarian, Milad; Mansouri Zangir, Seyed Behzad // Middle East Journal of Scientific Research;2013, Vol. 13 Issue 2, p183 

    Prevalence of urinary tract infections second to respiratory infections constitutes the highest statistics of infections among patients and has ranked first in terms of adult patients' visits with doctor. In infectious diseases such as urinary tract infections, doctors often have to treat the...

  • Honey as an Antimicrobial Agent Against Pseudomonas Aeruginosa Isolated from Infected Wounds. Shenoy, Vishnu Prasad; Ballal, Mamatha; Shivananda, P. G.; Bairy, Indira // Journal of Global Infectious Diseases;Apr2012, Vol. 4 Issue 2, p102 

    Background: As natural products garner attention in the medical field due to emergence of antibiotic resistant strains of bacteria, honey is valued for its antibacterial activity. Objective: Fifty strains of Pseudomonas aeruginosa isolated from infected wounds were evaluated for their...

  • Distribution of Nosocomial Organisms and their Resistance Patterns in the Intensive Care Unit of the University Hospital of the West Indies, Kingston, Jamaica. Nicholson, A. M.; Ledgister, S.; Williams, T.; Robinson, S.; Gayle, P.; Lindo, T.; Castle, D.; Shaw, K.; Moonah, S. // West Indian Medical Journal;Mar2009, Vol. 58 Issue 2, p142 

    Objectives: To determine the distribution and antibiotic susceptibility patterns of nosocomial pathogens in the Intensive Care Unit (ICU) at the University Hospital of the West Indies (UHWI). Methods: A retrospective review of the laboratory records of all ICU patients from 2002-2004 was done....

  • SUSCEPTIBILITY PATTERN OF COMMONLY ISOLATED MICROORGANISMS FROM CHRONIC SUPPURATIVE OTITIS MEDIA. Zakirullah, Zakirullah; Khan, Muhammad Ismail; Khan, Israr Uddin // Gomal Journal of Medical Sciences;Apr-Jun2015, Vol. 13 Issue 2, p123 

    Background: The knowledge of the local pattern of infection in chronic suppurative otitis media is essential to enable efficacious treatment for it. The objective of the study was to study the bacterial flora and their antimicrobial susceptibility pattern among isolated pathogens of chronic...

  • Gram-Stain Plus MALDI-TOF MS (Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry) for a Rapid Diagnosis of Urinary Tract Infection. Burillo, Almudena; Rodríguez-Sánchez, Belén; Ramiro, Ana; Cercenado, Emilia; Rodríguez-Créixems, Marta; Bouza, Emilio // PLoS ONE;Jan2014, Vol. 9 Issue 1, p1 

    Microbiological confirmation of a urinary tract infection (UTI) takes 24–48 h. In the meantime, patients are usually given empirical antibiotics, sometimes inappropriately. We assessed the feasibility of sequentially performing a Gram stain and MALDI-TOF MS mass spectrometry (MS) on urine...

  • Pyelonefrit: 190 Olgunun Retrospektif Analizi. Karakeçili, Faruk; Karadağ, Sanem; Erbay, Fatma; Yılmaz, Emel; Akalın, Halis; Özakin, Cüneyt; Özmen, Ahmet; Mıstık, Reşit; Helvacı, Safiye // Klimik Journal / Klimik Dergisi;Apr2010, Vol. 23 Issue 1, p10 

    Objective: In this study, we aimed to present the epidemiological, clinical and microbiological features of community acquired/ onset pyelonephritis cases followed in our clinic. Methods: One hundred ninety adult patients with pyelonephritis followed in our clinic between 1989-2008 were analysed...

  • Role of hospital stay and antibiotic use on Pseudomonas aeruginosa gastrointestinal colonization in hospitalized patients. Lepelletier, D.; Caroff, N.; Riochet, D.; Bizouarn, P.; Bourdeau, A.; Le Gallou, F.; Espaze, E.; Reynaud, A.; Richet, H. // European Journal of Clinical Microbiology & Infectious Diseases;Sep2006, Vol. 25 Issue 9, p600 

    The prospective cohort study presented here assessed the risk factors associated with Pseudomonas aeruginosa gastrointestinal colonization (PAGIC) in 933 patients hospitalized in five different wards in a French university hospital. A total of 195 patients were colonized. By logistic regression,...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics