Allergy & immunology
- REACTIVAREA INFECTIEI CU VIRUS HEPATITIC B LA BOLNAVII AFLATI ï¿½N TERAPIE BIOLOGICA. Ancuta, Ioan // Romanian Journal of Rheumatology;2012, Vol. 21 Issue 1, p28
Biologic therapy can induce HBV reactivation in both serologic profile patients (HBsAg positive or negative) with detectable HBV.DNA and negative HBsAb. In the last few years in Romania, a lot of cases with HBV reactivation were observed under biologic therapy. Tumor necrosis factor (TNFalfa)...
- Intratracheal instillation versus intratracheal inhalation:... Osier, M.; Baggs, R.B.; Oberdorster, G. // Environmental Health Perspectives Supplements;Sep97 Supplement 5, Vol. 105, p1265
Studies the roles that macrophage inflammatory protein-2 (MIP-2) and tumor necrosis factor alpha (TNF-alpha) may play in the observed differences in bronchoalveolar lavage (BAL) parameters. Methodology used; Analysis of the results; Conclusions.
- Effect of soluble interleukin-6 receptor a and interleukin-6 secreted by polymorphonuclear leukocytes on tumor necrosis factor-a expression and its production by peripheral blood mononuclear cells. Jablonska, E. // Mediators of Inflammation;Oct2002, Vol. 11 Issue 5, p325
Background: It has recently been shown that soluble interleukin-6 receptor (sIL-6R) alone or complexed with interleukin (IL)-6, besides their regulatory role in a wide variety of both normal and abnormal biologic reactions mediated by IL-6, could be an effective stimulator of the cell function....
- Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Schofield, Louis; Hewitt, Michael C.; Evans, Krystal; Siomos, Mary-Anne; Seeberger, Peter H. // Nature;8/15/2002, Vol. 418 Issue 6899, p785
Examines whether anti-glycosylphosphatidylinositol (GPI) vaccination could prevent pathology and fatalities in the Plasmodium berghei/rodent model of severe malaria. Use of tumor-necrosis factor-alpha production of macrophages as a biochemical marker of malarial endotoxin activity in vitro;...
- Cytokine-induced macrophage differentiation: a tale of 2 genes. Winston, Brent W.; Krein, Peter M. // Clinical & Investigative Medicine;Dec99, Vol. 22 Issue 6, p236
Macrophages are versatile cells found in every tissue in the body. They must perform a number of diverse cellular functions that allow them to kill invading microorganisms and neoplastic cells as well as produce growth factors involved in wound healing. Macrophages that develop these diverse...
- The Role of TNF-RII in Pathophysiology. // Fertility Weekly;7/21/2003, p11
Evaluates the expression of tumor necrosis factor-alpha-receptor type 2 in the endometrium of women with different degrees of endometriosis. Comparison of women with and without endometriosis; Measurement of the TNF-RII immunostaining; Reduction of endometrial glands and stroma.
- Altered Cytokine and Nitric Oxide Secretion In Vitro by Macrophages From Diabetic Type II-Like db/db Mice. Zykova, Svetlana N.; Jenssen, Trond G.; Berdal, Margrete; Olsen, Randi; Myklebust, Reidar; Seljelid, Rolf // Diabetes;Sep2000, Vol. 49 Issue 9, p1451
Studies the mechanics of macrophage dysfunction in human diabetes using type 2 db-db mice. Comparison of levels of tumor necrosis factor alpha and interleukin-1beta levels in diabetic versus control animals; High nitric oxide production; Altered morphological appearance of macrophages in diabetics.
- Anti-B7-1/B7-2 antibody elicits innate-effector responses in macrophages through NF-ÎºB-dependent pathway. Nooruddin Khan; Sheikh Ghousunnissa; SenthilKumar M. Jegadeeswaran; Dorairajan Thiagarajan; Seyed E. Hasnain; Sangita Mukhopadhyay // International Immunology;Apr2007, Vol. 19 Issue 4, p477
Blocking T cell co-stimulatory signals by anti-B7-1/B7-2 mAb is an attractive approach to treat autoimmune diseases. However, anti-B7-1/B7-2 mAb treatment is known to exacerbate autoimmune diseases through mechanisms not fully understood. Tumor necrosis factor alpha (TNF-Î±) and reactive...
- Macrophages: Interferons promote artery lesions. Bird, Lucy // Nature Reviews Immunology;Sep2010, Vol. 10 Issue 9, p616
The article reports on the study conducted by P. Goossens and colleagues which shows that myeloid type I interferons promote atherosclerosis by enhancing the recruitment of macrophages to lesions. The researchers found that the in vitro incubation of bone marrow derived macrophages with...