Stopping smoking improves semen parameters in smoker infertile men

Hosseini, M.; Jahan-abadi, Z.; Yonsefi, A.; Alborzi, M.
June 2014
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p118
Academic Journal
Introduction: Infertility affects up to 15% of the couples, which in 50% of cases, a male factor is involved. Several studies showed that smoking has an important negative impact on sperm production, motility and morphology. We investigated the prevalence of cigarette smoking among the infertile men referring to our infertility clinic and also the effect of smoking discontinuation on semen analysis parameters. Materials and Methods: Between September, 2009 to September, 2013, 235 infertile couples were enrolled in this cross-sectional study. History taking and physical examination were performed by experienced urologist with emphasis on the positive history of cigarette smoking. The patients who were successful in discontinuing cigarette smoking were re-examined after 3 months and the same evaluation including semen analysis were performed for each individual. Results: Of total 235 patients, 123 were smoker who encouraged stopping smoking. Giving up cigarette smoking in 78 patients resulted in 14-26% (mean: 19%) increase in sperm count as well as 8-27% (17%) improvement in sperm motility and 5 to 20% (14%) in sperm morphology. Also, without any accompanied therapeutic interventions, it resulted in pregnancy in 22 patients (28.2%) and delivery in 16 patients (20.5%). Conclusion: Although not all the mechanisms through which cigarette smoking could affect fertility are wellknown, every smoker must be encouraged to stop smoking, especially if a pregnancy is planned.


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