Pregnancy outcome of intracytoplasmic injection with epididymal and testicular sperm retrieval in azoospermic patients

Moein, M. R.; Esmail-Abad, S. Ghasemi; Ghasemzadeh, J.; Tabibnejad, N.
June 2014
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p116
Academic Journal
Introduction: Intra cytoplasmic sperm injection (ICSI) is anassisted reproductive technique for treatment of infertilify in azoospermicmen. It seems that pregnancy outcome in ICSI following percutaneous epididymalspermaspiration (PESA) is better than using testicular sperm retrieving from testis due to greater motility and befter morphology of epididymal spermatozoa. The objective was to determine clinical pregnancy outcome following ICSIwith epididymalspermcomparing to that of testicularspermin men with azoospermia. Materials and Methods: Sixty men with azoospermia who were candidate of ICSI selected. Sperm retrieval by PESA (n=30) or testicularspermextraction (TESE) (n=30) was performed. The number of embryos and live births were analyzed and evaluated. Results: No difference was seen in age and duration of infertility between groups. The number of embryos were notdifferent signiflcantly in two groups (3.14±2.28 vs. 3.67±2.89 p>0.05). However the live birth rate was higher in the PESA group compared with the TESE group (70.2% vs. 40%; p<0.05). Conclusion: Intracytoplasmic sperm injection using sperm from epididymis is more effective than testicular sperm injection and can successfully be performed to treat men with azoospermia.


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