TITLE

Antifertility effect of hydro-alcoholic extract of Fennel (Foeniculum vulgare Mill) seed in male rats

AUTHOR(S)
Kooti, W.; Mansori, E.; Ghasemiboroon, M.; Hasanzadeh Noohi, Z.; Asadi-Samani, M.; Azimi Resketi, M.; Foroutan Rad, M.
PUB. DATE
June 2014
SOURCE
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p107
SOURCE TYPE
Academic Journal
DOC. TYPE
Abstract
ABSTRACT
Introduction: Skyrocketing population is one of the main problems in modern communities. Today, study of anti-fertility effects of herbs has been considered because of the side effects of chemical medicines.This study is aimed to investigate the antifertility effect of chronically administered of foeniculim vulgare mill seed extract in male rats. Materials and Methods: In this experimental study, 40 Wistar rats divided into five groups of eight rats each. The control group received distilled water and the experimental groups were orally administrated 1ml fennel extract in four doses of 25, 70, 140, and 280 mg/kg/B.W daily for sixty days. After the last gavage, rat'sanesthetized; caudal parts of the right epididymis were used for sperm counting. After fixation of testis, tissue sections were prepared and studied microscopically for the evaluation of morphometric and histological changes. The data were analyzed by oneway ANOVA test using SPSS 15 software. Results: The number of spermatogonia and Sertoli cells decreased significantly in doses of 140 and 280 mg/kg compared with the control group (P<0.05). The number of primary spermatocyte and sperm count decreased significantly in the experimental groups when compared to control group (P<0.05). Furthermore Thickening of the basement membrane, cell apoptosis and irregular arrangement of germinal epithelium were observed in the experimental groups compared to the control group. Conclusion: Hydro-alcoholic extract of fennel seed in used doses could reduce reproductive activity in male rats and has anti fertility activity.
ACCESSION #
96841753

 

Related Articles

  • Good news about the pill. Stedman, Nancy // Redbook;Jun96, Vol. 187 Issue 2, p52 

    Reports on developments pertaining to the contraceptive pill. Study finding that there is no significant evidence of increased risk for breast cancer for women taking the pill for a long period of time; Pill for nursing mothers.

  • Emergency contraception. Abner, Allison // Essence (Essence);Mar1995, Vol. 25 Issue 11, p30 

    Reports on the existence of the morning-after pill (MAP), which can prevent pregnancy after unprotected sexual intercourse. Availability of the MAP through doctors and family-planning clinics; MAP as a combination of estrogen and progestin hormones; Dosages for pregnancy prevention; Need for...

  • Emergency Contraceptive Pills.  // Women's International Network News;Spring97, Vol. 23 Issue 2, p42 

    Announces the availability of an publication on contraceptive pills entitled `Emergency Contraceptive Pills.' Contact information.

  • New Zealand doctors resist emergency contraception. Williams, Carmel // BMJ: British Medical Journal (International Edition);2/24/96, Vol. 312 Issue 7029, p463 

    Reports on the resistance of general practitioners on the drug PC4, a pill designed for emergency contraception. Attributes of the emergency oral contraception; Lack of support form doctors and the pharmaceutical industry in New Zealand; Contention of general practitioners regarding he safety...

  • OB/GYN.  // Nurse Practitioners Prescribing Reference;Fall2011, Vol. 18 Issue 3, p224 

    The article offers information on several contraceptive drugs. It states that Megace ES is a drug for cachexia and anorexia or unexplained weight loss in patients with AIDS. It mentions the injectable contraception drug Depo-Provera from Pfizer Inc., whose contraindications include undiagnosed...

  • Ethinylestradiol/drospirenone.  // Reactions Weekly;4/24/2010, Issue 1298, p17 

    The article describes the case of a 20-year-old woman who experienced pulmonary embolism during treatment with ethinylestradiol-containing contraceptive pill, published in the January 14, 2010 issue of the journal "Tidsskrift for den Norske Laegeforening."

  • Opinion: Comment on Evaluation and Treatment of Cryptorchidism: AUA/AAP and Nordic Consensus Guidelines. Hadziselimovic, Faruk // Urologia Internationalis;Apr2016, Vol. 96 Issue 3, p249 

    The ultimate goal in the treatment of cryptorchidism is to achieve normal fertility. However, in a substantial number of cryptorchid males, early and apparently successful orchidopexy does not improve fertility as it does not address the underlying pathophysiological cause, namely, the impaired...

  • Emergency Contraception Pills--Need for Greater Access.  // HealthFacts;Aug2000, Vol. 25 Issue 8, p2 

    Reports on the need to make emergency contraception pills available over the counter.

  • Emergency Contraception: Safe, Effective, Neglected. Napoli, Maryann // HealthFacts;Sep2002, Vol. 27 Issue 9, p5 

    Focuses on the effectiveness of emergency contraceptive drugs in preventing pregnancy.

  • One implant, one year.  // International Family Planning Perspectives;Jun96, Vol. 22 Issue 2, p50 

    Reports that a hormonal contraceptive consisting of a single implant containing the progestin nomegesterol acetate provides effective protection against pregnancy for one year. Study conducted on the contraceptive in nine countries; Side effects of the implant.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics