Comparison of pregnancy rate per embryo transfer cycles when transferred frozen embryo was done on days 17,18 or 19

Torshizi, M. Mansouri; Naghavizadeh, M.; Khalilifar, H.; Islam, M. Fadavi; Bazri, Z.
June 2014
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p105
Academic Journal
Introduction: During the menstrual cycle the endometrium undergoes cyclic changes in preparation for implantation. In the follicular phase, the growing follicles produce increasing amounts of estradiol that will induce proliferative endometrial changes. Following ovulation, the corpus luteum produces progesterone that will initiate secretory changes. If implantation does not occur during the window of implantation, the endometrium will shed once the corpus luteum regresses. With certain endometrial abnormalities (e.g. Asherman's syndrome) that prevent normal endometrial changes from occurring, implantation rates are low and abortion rates are high (Schenker and Margalioth, 1982). Materials and Methods: This study was performed between 2012 and 2013 in Novin Infertility Treatment Center (Mashhad, Iran). We examined ICSI cycles of 1250 patients. All patients have embryo transfer in the same situation but in three different days. Results: Clinical and ongoing pregnancy rate (PR) andabortion rate were measured. Fertilization and implantation were similar between the groups. No difference was found regarding the number of transferred embryos (on day 2 or 3) and cryopreserved embryos, multiple pregnancies, abortion rates, transfer's drug protocol, transfer's Catheter or endometria's thickness between the groups. Pregnancy rate in group 2 that have embryo transfer on 18th day was more than 19lh, and in 19th is more than 17th day (p=0.04). Conclusion: Our results suggest increased endometrial thickness was associated with improved treatment outcome and significantly increased the chances of achieving a subsequent clinical and ongoing pregnancy. Women with transfer on 18th day have more chance than the other groups.


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