TITLE

Phytoestrogens and their beneficial role in women's health

AUTHOR(S)
Modarresi, M.
PUB. DATE
June 2014
SOURCE
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p78
SOURCE TYPE
Academic Journal
DOC. TYPE
Abstract
ABSTRACT
Introduction: Phytoestrogens are a group of biologically active plant substances with nonsteroidal structure but similar to that of estradiol, an endogenous estrogen. This structural similarity accounts for the ability of these compounds to bind to estrogen receptors in various cells and exert estrogenic or antiestrogenic effects. Phytoestrogens are found in many plant sources such as walnuts, soybeans, cereals (oats, barley, wheat, and rice), legumes (beans, lentils), berries, apples, carrots, ginseng, fennel, anise and flaxseed. This paper reviews the role of phytoestrogens in women's health. Materials and Methods: Online scientific sources were used to adjust this paper. These resources include Google Scholar, Advanced Search of Google, ScienceDirect, Scopus and en.bookfi.org. Results: Phytoestrogens are thought to act as both agonists and antagonists. The controlled clinical trials offer phytoestrogens as an alternative to conventional hormone replacement therapy (HRT) especially in postmenopausal women. The most important gynecologic effect of these agents is the treatment and control of the symptoms of menopause. The other beneficial effects of these compounds include prevention and treatment of osteoporosis and reduction of coronary heart diseases and cancers (such as breast, uterus and thyroid). Also evidence is emerging that phytoestrogens play a beneficial role in treatment of obesity and diabetes. Conclusion: Since long-term HRT can no longer be justified for disease prevention, women need alternative options to improve their quality of life and reduce their risk of heart disease, osteoporosis and breast cancer. Epidemiological and experimental evidence supports the importance of phytoestrogens in maintaining health and preventing disease in women.
ACCESSION #
96841674

 

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