Phytoestrogens and their beneficial role in women's health

Modarresi, M.
June 2014
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p78
Academic Journal
Introduction: Phytoestrogens are a group of biologically active plant substances with nonsteroidal structure but similar to that of estradiol, an endogenous estrogen. This structural similarity accounts for the ability of these compounds to bind to estrogen receptors in various cells and exert estrogenic or antiestrogenic effects. Phytoestrogens are found in many plant sources such as walnuts, soybeans, cereals (oats, barley, wheat, and rice), legumes (beans, lentils), berries, apples, carrots, ginseng, fennel, anise and flaxseed. This paper reviews the role of phytoestrogens in women's health. Materials and Methods: Online scientific sources were used to adjust this paper. These resources include Google Scholar, Advanced Search of Google, ScienceDirect, Scopus and en.bookfi.org. Results: Phytoestrogens are thought to act as both agonists and antagonists. The controlled clinical trials offer phytoestrogens as an alternative to conventional hormone replacement therapy (HRT) especially in postmenopausal women. The most important gynecologic effect of these agents is the treatment and control of the symptoms of menopause. The other beneficial effects of these compounds include prevention and treatment of osteoporosis and reduction of coronary heart diseases and cancers (such as breast, uterus and thyroid). Also evidence is emerging that phytoestrogens play a beneficial role in treatment of obesity and diabetes. Conclusion: Since long-term HRT can no longer be justified for disease prevention, women need alternative options to improve their quality of life and reduce their risk of heart disease, osteoporosis and breast cancer. Epidemiological and experimental evidence supports the importance of phytoestrogens in maintaining health and preventing disease in women.


Related Articles

  • WOMEN ON THE VERGE. Greenhalgh, Trisha // Accountancy;May97, Vol. 119 Issue 1245, p64 

    Focuses on hormone replacement therapy (HRT) as treatment for diseases associated with menopause. Risks and benefits of HRT; Focus on menopause and its impact on women's health.

  • It's as easy as HRT. Greenhalgh., Trisha // Accountancy;May2002, Vol. 129 Issue 1305, p64 

    Focuses on the patronage of hormone replacement therapy (HRT) among women in Great Britain. Side effects of HRT; Clinical trials on the effectivity of the treatment; Duration of treatment.

  • THE NEW HORMONE REPLACEMENT THERAPY. Mitchell, Terri // Life Extension;Dec2002, Vol. 8 Issue 12, p30 

    Discusses various aspects of estrogen and hormone replacement therapy. Definition of estrogen; Use of synthetic estrogen, such as Premarin, to treat menopausal symptoms; Benefits of phytoestrogens; Link of estrogen chemicals to breast cancer; Role of estrogens in preventing cancer, heart attack...

  • Effects of hormone therapy on quality of life in postmenopausal women with CAD differed according to menopausal symptoms. Haynes, Joan // ACP Journal Club;Nov/Dec2002, Vol. 137 Issue 3, p105 

    Discusses research being done on the effects of hormone therapy on the health-related quality of life in postmenopausal women with coronary artery disease. Reference to study by M.A. Hlatky and colleagues, published in the February 2002 issue of the 'Journal of American Medical Association';...

  • 2008 - Risk for cancer was still increased over 2 years after stopping hormone therapy. Cheung, Angela M. // ACP Journal Club;8/19/2008, Vol. 149 Issue 2, p9 

    The article focuses on a study regarding the health risks associated in postmenopausal women after stopping hormone therapy (HT) and presents the author's views on it. It describes the procedure of the study, which revealed that the risk of cancer increased in postmenopausal women, over 2 years...

  • US estrogen plus progestin HRT trial stopped due to increased risk of breast cancer, stroke and heart attack. Sibbald, Barbara // CMAJ: Canadian Medical Association Journal;8/6/2002, Vol. 167 Issue 3, p294 

    Reports that a U.S. trial of the risks and benefits of combined estrogen and progestin in healthy menopausal women has been stopped because long-term use increases the risk of breast cancer, stroke, and heart attacks. Benefits of the hormone therapy, including fewer hip fractures; Details of...

  • Update in Women’s Health 2006–2007. Zebrack, Jennifer R.; Gonzaga, Alda Maria; Neuner, Joan M.; Nattinger, Ann B. // JGIM: Journal of General Internal Medicine;Jan2008, Vol. 23 Issue 1, p93 

    The article presents abstracts on topics related to internal medicine including non-hormonal therapies for menopausal hot flashes, treatment of vasomotor symptoms of menopause with black cohosh multibotanicals, soy, hormone therapy, or placebo, and methods to screening for intimate partner...

  • HORMONES: ARE YOU A CANDIDATE?  // Prevention;Apr2007, Vol. 59 Issue 4, p165 

    The article consists of a chart to help women decide if they are candidates for hormone therapy for treatment of menopausal systems. Common symptoms and medical histories are matched against recommended treatments, including two separate forms of hormone therapy and avoiding their use. The chart...

  • Physical and mental health: changes during menopause transition. Mishra, Gita D.; Brown, Wendy J.; Dobson, Annette J. // Quality of Life Research;Jun2003, Vol. 12 Issue 4, p405 

    Objective: To measure changes in physical and mental health in six groups of women defined by menopausal status or use of hormone replacement therapy (HRT).Design: Longitudinal study with 2 years follow-up.Participants: Eight thousand six hundred and twenty...

  • PASS NOTES: HRT -- part 3. Newson, Louise // GP: General Practitioner;10/6/2003, p50 

    The latest U.S. findings showed that oestrogen-only hormone replacement therapy (HRT) increases the risk of ovarian cancer, especially if taken for more than 10 years. However, the increased risk is small and many women have oopherectomies at the time of their hysterectomy so this risk would...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics