TITLE

The effect of Madder root (Rubia) on testosterone in adult male rats

AUTHOR(S)
Najafi, A.; Raisi Dehkordi, Z.; Asadi, I.
PUB. DATE
June 2014
SOURCE
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p73
SOURCE TYPE
Academic Journal
DOC. TYPE
Abstract
ABSTRACT
Introduction: Madder is a foregoes plant from Rubiaceae family that historically originated from Ghafghaz and Near East. This plant was traditionally cultivated in the central and western regions of Iran. This study investigates the validity and/or invalidity of Madder root on enhancing the reproductive activity in male rats. Materials and Methods: In this trial, 33 adult male rats were randomized into three groups. The experimental groups received Rubia orally for 60 days in two different sublethal doses; 100 mg/kg as high dose and 50 mg/kg as low dose, whereas the control group received distilled water. Results: Significant decline in serum testosterone level was observed in both of the treated groups when compared with the control group. The respective levels in the low and high dose-receiving groups was 1.55±0.52 ng/ml and 1.26±0.34 ng/ml, respectively as compared to 4.23±1.03 ng/ml in the control group (pO.001). Conclusion: Based on the findings of the present study, it can be concluded that Rubia acts as an anti-fertility agent.
ACCESSION #
96841659

 

Related Articles

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics