C- Reactive protein (CRP) levels of serum and peritoneal fluid in women with endometriosis

Kianpour, M.; Nematbaksh, M.; Ahmady, M.
June 2014
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p72
Academic Journal
Introduction: Endometriosis is defined as the existence of endometrial-like tissue outside the uterus. Diagnosis of endometriosis is a challenging theme, and in spite the broad search for innovative laboratory tests and advances in imaging technologies, there are still no easy, non invasive diagnostic tests available. Due to inflammatory process of endometriosis, still CRP level may be target of initial screening. The aim of this study was to investigate CRP levels as a marker of inflammatory process in serum and peritoneal fluid of patients with endometriosis. Materials and Methods: In a case control study 179 women endometriosis (n=90), and without endometriosis (n=89), evaluated. The venous blood samples were obtained from all patients before laprascopy, and the peritoneal fluid samples were collected from pelvis before any manipulation. Unpaired T test was applied to compare the parameters between two groups. Results: It was found that there is no significant difference between the CRP serum level in women with endometriosis and infertile women without endometriosis. There was significant difference in peritoneal level of CRP between case and control groups. Conclusion: The findings suggested, measurement of this marker cannot be used to diagnose endometriosis. It is further recommended that a combination of different markers might be helpful in this regard, and other studies can investigate to find such useful markers.


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