The evaluation of infertility duration on the outcomes of IVF-ET

Ghasemian, F.; Zahiri, Z.; Azarnia, M.; Bahadori, M. H.; Asgharnia, M.
June 2014
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p60
Academic Journal
Introduction: To determine the effects of the women's infertility duration in the different age groups following IVF-ET. Materials and Methods: Infertile couples were divided into four groups according to their infertility duration (Gl: <5 years, n=193; G2: 6-10 years, n=176; G3: 11-15 years, n=87; and G4: >16 years, n=45) in 2011-2014. Then, the members of each group was considered as four groups based on their age (I: <35 yr, II: 35-37 yr, III: 38-40 yr, and IV: >40 yr). The rates of the normal fertilization, embryo quality, and clinical pregnancy were compared by the chi-square test. Results: The comparison among the groups of Gil, G2I, G3I, and G4I showed that the fertilization rate is not different among these groups (p>0.05) but the embryo quality and pregnancy rate are higher in Gil and G2I groups (p<0.05). These results repeated for GUI and G2II, and G1III and G2III groups. In the other hand, the fertilization and pregnancy rates were different and higher for GUV group (p<0.05). Conclusion: The increase of the infertility duration decreases the embryo quality and pregnancy rate. It looks that the increase of infertility duration of couples, the rate of stress, unhappiness, and irritable was increased. Of course, due to the low number of infertile couples in the ages lower than 37 yr and the infertility duration of higher than 16 yr, we were unable to collect sufficient data. Therefore, we were unable to compare its effect in these groups.


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