Effect of soy phytoestrogen on metabolic and hormonal disturbance of women with polycystic ovary syndrome

Khani, B.; Mehrabian, F.
June 2014
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p12
Academic Journal
Introduction: Infertility is an increasing medical and social problem. Recently, In Vitro Fertilization (IVF) has become a common and accessible treatment for a wide variety of indications that have variable outcomes. NK cells have been identified as relevant immunological factors involved in reproductive success or failure. The aim of this study was to compare the percentage of peripheral blood CD56 (+) (CD56 (dim) and CD56 (bright)) cells and the level of NK cell in patients with IVF failure with those of successful IVF control women. Materials and Methods: We assessed the level of CD56dim CD16+ and CD56 bright CD16 cells in 50 women under IVF treatment and were comparing between successful IVF and IVF failure with the flow cytometry examination. Results: 58% of women did not response to IVF therapy and 42% had successful IVF, the level of CD56dim CD16+ cells in women with IVF failure was significantly higher than successful IVF(p<0.0001) but the level of CD56bright CD 16 cells was not significantly different between women with IVF failure and successful IVF (p=0.28). Conclusion: The results of the present study demonstrated that the level of CD56 dim CD16+ cells is associated with pregnancy loss in women with IVF failure but the level of CD56 bright CD 16 cells was not significantly different between women with IVF failure and successful IVF. However further study with more sample size are need to be done. We suggest considering treatment option for women undergoing repeated IVF failure with increased percentage of CD56 (dim) cells and the level of peripheral blood NK cell.


Related Articles

  • Implicación clínica y frecuencia del hallazgo incidental de endometriosis durante la captura ovular. Anguas, Julián Ruiz; Mondragón, Esperanza Carballo; Jaen, Everardo Anta; Monterrosas, Leonor Durán; Ambe, Alberto Kably // Ginecologia y Obstetricia de Mexico;mar2007, Vol. 75 Issue 3, p121 

    Background: Endometriosis is a clinical disease that is associated with poor outcomes in in vitro fertilization (IVF) programs with a decrease in oocyte retrieval, oocyte quality, implantation and pregnancy rates. When an endometrioma is diagnosed, it is indicated to remove endometrial cysts by...

  • Elevated CD 56 dim and CD 56 bright natural killer cells in peripheral blood of women with IVF failures. Kazerooni, M.; Mardanian, F. // Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p12 

    Introduction: Some studies support the concept that NK cells play an important role in the success or failure of embryo implantation. Some couples suffer from infertility of unknown cause. In vitro fertilization (IVF) is one of the useful treatment methods used for treatment of this type for...

  • A NOVEL OPERATIVE TREATMENT OF SEVERE ADENOMYOSIS PRIOR TO EMBRYO TRANSFER. Osada, H. // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Oct2010 S3 Supplemen, Vol. 20, pS14 

    Introduction: Severe case of adenomyosis is not only a cause of infertility, but may include severe dysmenorrhea, thus may interfere with a woman's well-being. Routine conservative surgery for adenomyosis involves a wedge resection of the involved uterine tissue, followed by approximating the...

  • Contemporary genetic technologies and female reproduction.  // Human Reproduction Update;Nov2011, Vol. 17 Issue 6, p829 

    BACKGROUND The Fifth Evian Annual Reproduction (EVAR) Workshop Meeting discussed knowledge regarding contemporary genetics in female reproduction. METHODS Specialist reproductive medicine clinicians and geneticists delivered presentations based on published literature and current research. The...

  • HPV Does Not Cause Infertility.  // Fertility Weekly;1/20/2003, p6 

    Presents a study on the prevalence of genital human papillomavirus infection in infertile women in Sweden. Comparability of viral level in fertile females; Determination of abnormal cytology; Success of in vitro fertilization.

  • Sensitivity of Women to Luteinizing Hormone.  // Fertility Weekly;6/23/2003, p7 

    Compares the sensitivity of the granula cells of women with endometriosis to luteinizing hormone (LH) with that of the cells of women without the condition. Impact of the disease on oocyte fertilization rates in vitro in women; Cycles stimulated with exogenous gonadotropins; Abnormalities of...

  • Role of Latent Genital Tuberculosis in Repeated IVF Failure in the Indian Clinical Setting. Dam, Purvita; Shirazee, Hasibul Hasan; Goswami, Sourendra Kanta; Ghosh, Sanghamitra; Ganesh, Ashalatha; Chaudhury, Koel; Chakravarty, Baidyanath // Gynecologic & Obstetric Investigation;May2006, Vol. 61 Issue 4, p223 

    Genital tuberculosis is reported to be a major pelvic factor causing infertility in Indian women and often exists without any apparent signs and symptoms. The role of latent tuberculosis in repeated IVF failure in unexplained infertility is examined. 81 women with unexplained infertility having...

  • gynatresia.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p995 

    A definition of the term "gynatresia," which refers to the occlusion of the female reproductive tract, is presented

  • gynecological operative procedures.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p995 

    An encyclopedia entry for "gynecological operative procedures," which refers to the surgery of the female reproductive tract, is presented.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics