TITLE

Uterine fibroid embolization and pregnancy outcome

AUTHOR(S)
Hatami, M.
PUB. DATE
June 2014
SOURCE
Iranian Journal of Reproductive Medicine;Jun2014 Supplement, Vol. 12, p10
SOURCE TYPE
Academic Journal
DOC. TYPE
Abstract
ABSTRACT
Introduction: Uterine fibroids are common in reproductive age. Around 10-20% of women who have fibroid require treatment and 1%-2% of infertility in women is due to fibroids. To determine and compare fibroid treatment effects on fertility, and to review the role of uterine fibroid embolization (UFE) in pregnancy outcome. Materials and Methods: A literature review was undertaken to include the published articles about UFE between 1995-2014. Results: Gn-RH agonists treat fibroids by blocking the estrogen and progesterone releasing, cause a postmenopausal situation and decrease the fibroid size. Usual surgical procedures contain hysterectomy and abdominal myomectomy. Minimally invasive procedures like laparoscopic or robotic myomectomy arc less invasive. Hysteroscopic myomectomy, endometrial ablation and sub mucosal fibroid resection are vaginally options. New non-invasive method, Magnetic Resonance Guided Focused Ultrasound is under research. UFE is a less invasive procedure, preserve uterus and requires a small incision into the femoral artery for using microspheres or polyvinyl alcohol particles to block the blood supply to the uterine fibroids, causing them to shrink. Numerous successful pregnancies after UFE have been reported. In Ravina's study, among 184 women who had UFE, 12 unexpected pregnancies occurred. McLucas reported that 22 of the 28 pregnancies after UFE were normal full term pregnancy. He compared the pregnancy rate of his cohort study after UFE (47.7%) to abdominal myomectomy where was in the range of 10-46%, laparoscopic myomectomy (16-33%), and hysteroscopic myomectomy (8-35%). Conclusion: UFE as an acceptable fibroid treatment should be considered in young women, as benefits, risks and further fertility evaluation is suggested.
ACCESSION #
96841499

 

Related Articles

  • Magnetic resonance-guided focused ultrasound surgery (MRgFUS) treatment for uterine fibroids. Abdullah, B. J. J.; Subramaniam, R. V.; Omar, S. S.; Wragg, P.; Ramli, N.; Wui, A. L.; Lee, C. C.; Yusof, Y. // Biomedical Imaging & Intervention Journal;Mar2010, Vol. 6 Issue 1, p1 

    Magnetic Resonance-guided focused Ultrasound Surgery (MRgFUS) is gaining popularity as an alternative to medical and surgical interventions in the management of symptomatic uterine fibroids. Studies have shown that it is an effective non-invasive treatment with minimal associated risks as...

  • Ultrasound in the Investigation of Pelvic Pain. Dixo, Anne-Marie // Ultrasound;2005, Vol. 13 Issue 1, p30 

    An ultrasound examination is commonly requested during the evaluation of women presenting for investigation of pelvic pain. This paper reviews the common causes of pelvic pain describing the associated clinical signs and symptoms, the typical ultrasound appearances and the role of ultrasound in...

  • Fibroids in Pregnancy: What You Need to Know. Blumenfeld, Yair // Contemporary OB/GYN;Dec2014, Vol. 59 Issue 12, p38 

    The article presents questions and answers related to fibroids in pregnancy including ho common it is, the problems it can cause during pregnancy, and the available therapies for fibroid-related pain.

  • Editor's Choice. Steirteghem, André Van // Human Reproduction;Dec2009, Vol. 24 Issue 12, p2971 

    The article discusses various reports published within the issue, including one about the production of offspring in mice from a female germline stem-cell line derived from neonatal ovaries and another on the risk of adverse pregnancy outcomes in pregnant women with uterine leiomyomata.

  • Leiomyoma of the bladder presenting as acute urinary retention in a female patient: urodynamic analysis of lower urinary tract symptom; a case report. Matsushima, Masashi; Asakura, Hirotaka; Sakamoto, Hirofumi; Horinaga, Minoru; Nakahira, Yoko; Yanaihara, Hitoshi // BMC Urology;2010, Vol. 10, p13 

    Background: Most bladder tumors are derived from the urothelium. Benign mesenchymal tumors are rare. Leiomyoma of the bladder is the most common benign neoplasm. We present a case of leiomyoma of the bladder presenting with acute urinary retention in a female patient and report on the...

  • MR-guided ultrasound surgery: Effective treatment for uterine fibroids?  // Contemporary OB/GYN;Oct2007, Vol. 52 Issue 10, p23 

    This article discusses findings of a study, which investigated the efficacy of magnetic resonance-guided ultrasound surgery in treating uterine fibroids. This type of surgery may be performed without general anesthesia, with no recovery period, and which leaves the uterus intact. However, the...

  • Conference Abstracts . . . January 10, 2005.  // Fertility Weekly;1/10/2005, p11 

    The article presents abstracts of various research papers published in the journal "Fertility Weekly". One of the abstract focuses on growth factor secretion by somatic cell monolayers, which may potentially help struggling embryos to develop and activate their genome. Autologous endometrial...

  • Treatment of fibroids via uterine artery occlusion (uterine artery embolization and Doppler-guided uterine artery occlusion): potential role in today’s armamentarium. Brill, Andrew // Archives of Gynecology & Obstetrics;Oct2009, Vol. 280 Issue 4, p513 

    Uterine fibroids, the most common benign tumors of the female reproductive system, are the most common indication for hysterectomy. However, this procedure is not the ideal treatment for many women including those who desire to preserve their fertility or simply do not want to undergo surgery....

  • Pregnancy, Parturition, and Prostaglandins: Defining Uterine Leiomyomas. Cesen-Cummings, Kimberley; Copland, John A.; Barrett, J. Carl; Walker, Cheryl L.; Davis, Barbara J. // Environmental Health Perspectives Supplements;Oct2000 Supplement 5, Vol. 108, p817 

    Proposes the hypothesis that uterine leiomyomas mimic a differentiated myometrial cell at pregnancy and exhibits a hypersensitivity to sex steroid hormones that prevents the cells from responding to normal apoptotic or dedifferentiation signals and from returning to a nongravid phenotype. ...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics