Eosinophilic pneumonitis secondary to pegylated interferon alpha-2b and/or ribavirin therapy

Hoffman, Seth D; Hammadeh, Rasheed; Shah, Nikunj
September 2003
American Journal of Gastroenterology;Sep2003 Supplement, Vol. 98, pS152
Academic Journal
An abstract of the article "Eosinophilic Pneumonitis Secondary to Pegylated Interferon Alpha-2B and/or Ribavirin Therapy," by Seth D. Hoffman, Rasheed Hammadeh and Nikunj Shah is presented.


Related Articles

  • The Role of Interferon-g in Murine Pneumococcal Pneumonia. Rijneveld, Anita W.; Lauw, Fanny N.; Schultz, Marc J.; Florquin, Sandrine; Te Velde, Anje A.; Speelman, Peter; Van Deventer, Sander J.H.; Van Der Poll, Tom // Journal of Infectious Diseases;1/1/2002, Vol. 185 Issue 1, p91 

    To determine the role of interferon (IFN)-γ in pneumonia, IFN-γ receptor-deficient (IFN-γ R[sup -/-]) and 129/Sv (wild-type [wt]) mice were inoculated intranasally with Streptococcus pneumoniae. Although mortality did not differ between the groups 48 h after inoculation, IFN-γ R[sup...

  • Organizing Pneumonia Associated with Pegylated Interferon α and Ribavirin Therapy. Chopra, Amit; Marak, Creticus; Alappan, Narendrakumar; Shim, Chang // Case Reports in Pulmonology;1/29/2015, Vol. 2015, p1 

    Hepatitis C virus infection is the leading cause of chronic liver disease in the United States of America. Pegylated interferon α and ribavirin combination is the mainstay of treatment. Severe pulmonary toxicities are rarely reported. We report here a case of severe form of organizing...

  • NK and NKT Cell Depletion Alters the Outcome of Experimental Pneumococcal Pneumonia: Relationship with Regulation of Interferon-γ Production. Christaki, Eirini; Diza, Evdoxia; Giamarellos-Bourboulis, Evangelos J.; Papadopoulou, Nikoletta; Pistiki, Aikaterini; Droggiti, Dionysia-Irini; Georgitsi, Marianna; Machova, Alzbeta; Lambrelli, Dimitra; Malisiovas, Nicolaos; Nikolaidis, Pavlos; Opal, Steven M. // Journal of Immunology Research;5/31/2015, Vol. 2015, p1 

    Background. Natural killer (NK) and natural killer T (NKT) cells contribute to the innate host defense but their role in bacterial sepsis remains controversial. Methods. C57BL/6 mice were infected intratracheally with 5 × 105 cfu of Streptococcus pneumoniae. Animals were divided into...

  • Interferon-gamma coordinates CCL3-mediated neutrophil recruitment in vivo. Bonville, Cynthia A.; Percopo, Caroline M.; Dyer, Kimberly D.; Jiliang Gao; Prussin, Calman; Foster, Barbara; Rosenberg, Helene F.; Domachowske, Joseph B. // BMC Immunology;2009, Vol. 10, Special section p1 

    Background: We have shown previously that acute infection with the respiratory pathogen, pneumonia virus of mice (PVM), results in local production of the proinflammatory chemokine, CCL3, and that neutrophil recruitment in response to PVM infection is reduced dramatically in CCL3 -/- mice....

  • Toll-Like Receptor Activation during Cutaneous Allergen Sensitization Blocks Development of Asthma through IFN-Gamma-Dependent Mechanisms. Haapakoski, Rita; Karisola, Piia; Fyhrquist, Nanna; Savinko, Terhi; Lehtimäki, Sari; Wolff, Henrik; Lauerma, Antti; Alenius, Harri // Journal of Investigative Dermatology;Apr2013, Vol. 133 Issue 4, p964 

    Toll-like receptors (TLRs) are pattern-recognition receptors that have a pivotal role as primary sensors of microbial products and as initiators of innate and adaptive immune responses. We investigated the role of TLR2, TLR3, and TLR4 activation during cutaneous allergen sensitization in the...

  • Study Shows Why Pneumonia is More Deadly After Flu Infection. Breindl, Anette // BioWorld Today;6/11/2009, Vol. 20 Issue 111, p1 

    The article discusses research which revealed that bacterial pneumonia is the cause of mortality among patients with flu. It references a study by Jane Deng and colleagues published in the June 1, 2009 issue of the "Journal of Clinical Investigation." Molecular details of how flu makes patients...

  • Peginterferon-α-2b.  // Reactions Weekly;5/3/2008, Issue 1200, p26 

    The article describes the case of a 49-year-old man who developed organising pneumonia during treatment with peginterferon-α-2b for chronic hepatitis C. Six months after receiving the treatment, the patient experienced two weeks of progressive dyspnoea, dry cough and fever. Information is...

  • Peginterferon-α/ribavirin.  // Reactions Weekly;5/30/2009, Issue 1254, p34 

    The article describes the case of a 50-year-old man who experienced desquamative interstitial pneumonia (DIP) while receiving peginterferon-α and ribavirin for chronic hepatitis C virus infection and inflammatory activity. Results of chest x-ray and computed tomography (CT) scan are cited....

  • Induction of Type I Interferon Signaling Determines the Relative Pathogenicity of Staphylococcus aureus Strains. Parker, Dane; Planet, Paul J.; Soong, Grace; Narechania, Apurva; Prince, Alice // PLoS Pathogens;Feb2014, Vol. 10 Issue 2, p1 

    The tremendous success of S. aureus as a human pathogen has been explained primarily by its array of virulence factors that enable the organism to evade host immunity. Perhaps equally important, but less well understood, is the importance of the intensity of the host response in determining the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics