TITLE

A new HLA allele (A*0201) accounts for DQ2/DQ8 negative genome screening in celiac disease patients

AUTHOR(S)
Bizzarri, Barbara; Drago, Sandro; Pierro, Mariarosaria Di; Sapone, Anna; Kryszak, Debbye; Catassi, Carlo; Fasano, Alessio
PUB. DATE
September 2003
SOURCE
American Journal of Gastroenterology;Sep2003 Supplement, Vol. 98, pS229
SOURCE TYPE
Academic Journal
DOC. TYPE
Abstract
ABSTRACT
An abstract of the article "A new HLA allele (A*0201) accounts for DQ2/DQ8 negative genome screening in celiac disease patients," by Barbara Bizzari and colleagues is presented.
ACCESSION #
66954820

 

Related Articles

  • HLA-DR typing in coeliac disease: evidence for genetic heterogeneity. Ellis, A.; Taylor, C.J.; Dillon-Remmy, M.; Woodrow, J.C.; McConnell, R.B. // British Medical Journal (Clinical Research Edition);12/8/1984, Vol. 289 Issue 6458, p1571 

    Focuses on the genetic aspects of celiac disease by examining the HLA-DR antigens of patients in Great Britain. Association of celiac disease with DR3 and DR7 antigens; Evidence on the genetic heterogeneity of childhood and adult celiac disease; Comparison on the frequency of specific HLA...

  • Cytokine genotyping (TNF and IL-10) in patients with celiac disease and selective IgA deficiency. Cataldo, F.; Lio, D.; Marino, V.; Scola, L.; Crivello, A.; Mulè, A.M.; Corazza, G.R. // American Journal of Gastroenterology;Apr2003, Vol. 98 Issue 4, p850 

    : ObjectiveSelective IgA deficiency (IgAD) and celiac disease (CD) are frequently associated and share the ancestral haplotype human leukocyte antigen (HLA)-8.1, which is characterized by a peculiar cytokine profile. The aim of this study was to evaluate the role of tumor necrosis factor (TNF)...

  • JUNK FOOD OR JUNK GENOME. BILBAO, JOSE RAMON; CASTELLANOS-RUBIO, AINARA // Laboratory News;Nov2016, p22 

    The article focuses on the coeliac disease (CD) which is an immune-mediated enteropathy caused by ingested gluten which develops in genetically susceptible individuals and mentions that human leukocyte antigen (HLA) are not sufficient to develop coeliac disease.

  • HLA-DQ typing in the diagnosis of celiac disease. Kaukinen, Katri; Partanen, Jukka; Mäki, Markku; Collin, Pekka // American Journal of Gastroenterology;Mar2002, Vol. 97 Issue 3, p695 

    OBJECTIVE:More than 95% of celiac patients share the major histocompatibility complex II class human leukocyte antigen (HLA) DQ2 or DQ8 haplotype; patients negative for both types are unlikely to suffer from celiac disease. Our aim was to investigate whether HLA-DQ2 and -DQ8 typing is helpful...

  • Defining the contribution of the HLA region to cis DQ2-positive coeliac disease patients. van Belzen, M. J.; Koeleman, B. P. C.; Crusius, J. B. A.; Meijer, J. W. R.; Bardoel, A. F. J.; Pearson, P. L.; Sandkuijl, L. A.; Houwen, R. H. J.; Wijmenga, C. // Genes & Immunity;May2004, Vol. 5 Issue 3, p215 

    The major genetic susceptibility to coeliac disease is contributed by the human leukocyte antigen (HLA) region. The primary association is with the HLA-DQ2 molecule, encoded by the DQA1*05 and DQB1*02 alleles, which is expressed by over 90% of patients. The aim of our study was to perform an...

  • Linkage analysis of HLA and candidate genes for celiac disease in a North American family-based study. Neuhausen, Susan L.; Feolo, Michael; Farnham, James; Book, Linda; Zone, John J. // BMC Medical Genetics;2001, Vol. 2, p12 

    Background: Celiac disease has a strong genetic association with HLA. However, this association only explains approximately half of the sibling risk for celiac disease. Therefore, other genes must be involved in susceptibility to celiac disease. We tested for linkage to genes or loci that could...

  • Celiac disease and HLA DQ in patients with IgA nephropathy Collin, Pekka; Syrjänen, Jaana; Partanen, Jukka; Pasternack, Amos; Kaukinen, Katri; Mustonen, Jukka // American Journal of Gastroenterology;Oct2002, Vol. 97 Issue 10, p2572 

    OBJECTIVES:Despite some reports on an association between celiac disease and IgA nephropathy, the evidence is still sparse. Celiac disease is strongly associated with the HLA DQ2 and DQ8 haplotypes, which might explain the potential risk of patients to contract various autoimmune conditions. In...

  • The Down syndrome, CD link.  // GIG Newsletter;Fall2008, Vol. 31 Issue 4, p30 

    The article discusses research on the link between Down syndrome and celiac disease among children, with reference to a study published in the September 22, 2008 issue of the "Journal of Pediatrics." Results showed that 63 children were positive of human leukocyte antigen HLA-DQ2 or HLA-DQ8 and...

  • Between Celiac Disease and Irritable Bowel Syndrome: The “No Man's Land” of Gluten Sensitivity. Verdu, Elena F.; Armstrong, David; Murray, Joseph A. // American Journal of Gastroenterology;Jun2009, Vol. 104 Issue 6, p1587 

    The repertoire of gastrointestinal (GI) symptoms is finite; however, the etiologies and mechanisms underlying symptom generation and perception are diverse and, in many cases, unknown. This review examines the clinical and experimental evidence exploring the putative relationship between gluten...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics