TITLE

Infections and inflammatory mechanisms in chronic obstructive pulmonary disease exacerbations

PUB. DATE
December 2005
SOURCE
Thorax;Dec2005 Supplement 2, Vol. 60, pii83
SOURCE TYPE
Academic Journal
DOC. TYPE
Abstract
ABSTRACT
The article presents abstracts on chronic obstructive pulmonary disease exacerbations. They include "The Effect of Levofloxazin on Neutrophilic Airway Inflammation in Stable State Chronic Obstructive Pulmonary Disease: A Randomised, Double Blind, Placebo Controlled Trial," by R. Siva, W. Monteiro, D. Parker, M. Shelley, B. Horgadon, S. McKenna, C.E. Brightling, M. Barer and I.D. Pcivord, "Neutrophil Adhesion Molecules in an Experimental Model of Rhinovirus Induced Chronic Obstructive Pulmonary Disease Exacerbation," by P. Mallia, S. Message, V. Laza-Stanca, M. Contoli, T. Kebadze and S. Johnston, and "Establishing Primary Cultures of Nasal Epithelial Cells From Nasal Brushings," by C.M. McDougall.
ACCESSION #
19836649

 

Related Articles

  • The Effect of Azithromycin in Adults with Stable Neutrophilic COPD: A Double Blind Randomised, Placebo Controlled Trial. Simpson, Jodie L.; Powell, Heather; Baines, Katherine J.; Milne, David; Coxson, Harvey O.; Hansbro, Philip M.; Gibson, Peter G. // PLoS ONE;Aug2014, Vol. 9 Issue 8, p1 

    Background: Chronic Obstructive Pulmonary Disease (COPD) is a progressive airway disease characterised by neutrophilic airway inflammation or bronchitis. Neutrophilic bronchitis is associated with both bacterial colonisation and lung function decline and is common in exacerbations of COPD....

  • Asthma: alternative anti-inflammatory agents needed for patient subgroup.  // PharmaWatch: Monthly Review;Mar2005, Vol. 4 Issue 3, p26 

    The article presents a study conducted by the European Network for Understanding Mechanisms of Severe Asthma, concerning the role of the neutrophil in the pathogenesis of asthma. It has suggested that severe asthma is a different disease to mild-moderate disease. The presence of neutrophilic...

  • Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers. Willemse, Brigitte W. M.; Hacken, Nick H. T. Ten; Rutgers, Bea; Postma, Dirkje S.; Timens, Wim // Respiratory Research;2005, Vol. 6, p38 

    Background: Inflammation in the airways and lung parenchyma underlies fixed airway obstruction in chronic obstructive pulmonary disease. The exact role of smoking as promoting factor of inflammation in chronic obstructive pulmonary disease is not clear, partly because studies often do not...

  • Pairwise Comparison of Levalbuterol versus Racemic Albuterol in the Treatment of Moderate-to-Severe Asthma. Pleskow, Warren W.; Nelson, Harold S.; Schaefer, Kendyl; Claus, Raymond; Roach, James M. // Allergy & Asthma Proceedings;Nov/Dec2004, Vol. 25 Issue 6, p429 

    The object of this study is a post hoc pairwise comparison of levalbuterol versus racemic albuterol for asthma in a multicenter, double-blind, randomized, placebo-controlled clinical trial. The participants are patients ⩾12 years of age (n = 362) with FEV1 45-70% of predicted. The patients...

  • Effect of Yufeining (...) on Induced Sputum Interleukin-8 in Patients with Chronic Obstructive Pulmonary Disease at the Stable Phase. Hong Min-li; Yang Guo-zong; Chen Wen-xi; Gao Ling-yun; Cai Shao-hang; Dai Shun-zhen // Chinese Journal of Integrative Medicine;Sep2005, Vol. 11 Issue 3, p179 

    Objective: To evaluate the effect of Yufeining (...), a traditional Chinese medicine, on induced sputum interleukin-8 (IL-8) in patients with chronic obstructive pulmonary disease (COPD) at the stable phase. Methods: Thirty-six patients with COPD were divided into trial group (18 cases) and...

  • Human Neutrophil Peptides sputum levels in symptomatic smokers and COPD patients. PAONE, G.; CONTI, V.; LEONE, A.; SCHMID, G.; PUGLISI, G.; GIANNUNZIO, G.; TERZANO, C. // European Review for Medical & Pharmacological Sciences;2011, Vol. 15 Issue 5, p556 

    Background and Objectives: Human Neutrophil Peptides (HNP) are major neutrophils' products which may contribute to the airway inflammation and lung remodelling during chronic obstructive pulmonary disease (COPD). We aimed to assess whether HNP sputum concentrations could be used as indicators of...

  • Inflammatory cells in the airways in COPD. O'Donnell, R.; Breen, D.; Wilson, S.; Djukanovic, R. // Thorax;May2006, Vol. 61 Issue 5, p448 

    Airway inflammation is central to the pathogenesis of both airway remodelling and parenchymal destruction in chronic obstructive pulmonary disease (COPD). Neutrophils, macrophages, and CD8+ T lymphocytes have been implicated in a number of studies, but a detailed profile of disease-phenotype...

  • Sputum neutrophils as a biomarker in COPD: findings from the ECLIPSE study. Singh, Dave; Edwards, Lisa; Tal-Singer, Ruth; Rennard, Stephen // Respiratory Research;2010, Vol. 11, p77 

    Introduction: The percentage of neutrophils in sputum are increased in COPD patients, and may therefore be a biomarker of airway inflammation. We studied the relationships between sputum neutrophils and FEV1, health status, exacerbation rates, systemic inflammation and emphysema, and long term...

  • Cigarette smoke enhances human rhinovirus-induced CXCL8 production via HuR-mediated mRNA stabilization in human airway epithelial cells. Hudy, Magdalena H.; Proud, David // Respiratory Research;Aug2013, Vol. 14 Issue 8, p1 

    Background: Human rhinovirus (HRV) triggers exacerbations of asthma and chronic obstructive pulmonary disease (COPD). Cigarette smoking is the leading risk factor for the development of COPD and 25% of asthmatics smoke. Smoking asthmatics have worse symptoms and more frequent hospitalizations...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics