Host-pathogen interaction in the lung

December 2004
Thorax;Dec2004 Supplement, Vol. 59, p16
Academic Journal
This article presents abstracts of several medical studies conducted in the field of host-pathogen interaction in lungs. In one study it was hypothesised that asthmatic bronchial epithelial cells (BEC) would have a deficient type I interferon response to infection with RV-16 and this would relate to increased susceptibility to infection. BEC were obtained by bronchial brushings from subjects with asthma and healthy non-atopic controls and grown to confluence. The study suggested a novel use for type I interferons in the treatment or prevention of virus-induced asthma exacerbations.


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