Neurogastroenterology/motility free papers

April 2005
Gut;Apr2005 Supplement 2, Vol. 54, pA18
Academic Journal
The article presents information on abstracts related to neurogastroenterology. According to an abstract cilansetron is efficacious in relieving bowel habit related symptoms in irritable bowel syndrome with diarrhoea predominance. Diarrhoea and abdominal pain/discomfort are key symptoms of irritable bowel syndrome with diarrhea predominance (IBS-D). Cilansetron, a new 5-1-113 receptor antagonist, demonstrated adequate relief of lBS symptoms in a significantly greater proportion of IBS-D patients compared with placebo. This double blind, placebo controlled, six month multi-national study was designed to assess the efficacy of cilansetron on adequate relief of lBS symptoms in Rome defined IBS-D patients. Responders to treatment were defined as patients who reported adequate relief of abnormal bowel habits for greater than or equal to 50% of their weekly diary responses.


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