TITLE

Neurogastroenterology/motility free papers

PUB. DATE
April 2005
SOURCE
Gut;Apr2005 Supplement 2, Vol. 54, pA18
SOURCE TYPE
Academic Journal
DOC. TYPE
Abstract
ABSTRACT
The article presents information on abstracts related to neurogastroenterology. According to an abstract cilansetron is efficacious in relieving bowel habit related symptoms in irritable bowel syndrome with diarrhoea predominance. Diarrhoea and abdominal pain/discomfort are key symptoms of irritable bowel syndrome with diarrhea predominance (IBS-D). Cilansetron, a new 5-1-113 receptor antagonist, demonstrated adequate relief of lBS symptoms in a significantly greater proportion of IBS-D patients compared with placebo. This double blind, placebo controlled, six month multi-national study was designed to assess the efficacy of cilansetron on adequate relief of lBS symptoms in Rome defined IBS-D patients. Responders to treatment were defined as patients who reported adequate relief of abnormal bowel habits for greater than or equal to 50% of their weekly diary responses.
ACCESSION #
16567954

 

Related Articles

  • A Dose-Ranging, Phase II Study of the Efficacy and Safety of Alosetron in Men with Diarrhea-Predominant IBS. Chang, Lin; Ameen, Vanessa Z.; Dukes, George E.; McSorley, David J.; Carter, Eric G.; Mayer, Emeran A. // American Journal of Gastroenterology;Jan2005, Vol. 100 Issue 1, p115 

    BACKGROUND: A randomized, double blind, placebo-controlled dose-ranging study was conducted to assess the efficacy of alosetron in men with diarrhea-predominant irritable bowel syndrome (IBS).METHODS: Six hundred and sixty-two men were randomized to treatment with alosetron 0.5, 1.0, 2.0, 4.0...

  • Treatment of Diarrhea-Predominant Irritable Bowel Syndrome with Traditional Chinese Herbal Medicine: A Randomized Placebo-Controlled Trial. Leung, Wai K.; Wu, Justin C.Y.; Liang, S.M.; Chan, L.S.; Chan, Francis K.L.; He Xie; Fung, Sara S.L.; Hui, Aric J.; Wong, Vincent W.S.; Chun-Tao Che; Sung, Joseph J.Y. // American Journal of Gastroenterology;Jul2006, Vol. 101 Issue 7, p1574 

    BACKGROUND: As there is no effective treatment for irritable bowel syndrome (IBS), many patients turn to traditional Chinese medicine (TCM) for possible cure. We investigated the therapeutic efficacy of an ancient herbal Chinese formula in patients with diarrhea-predominant IBS. METHODS: This...

  • Lack of Efficacy of Saccharomyces Boulardii in Diarrhea Predominant Irritable Bowel Syndrome -- a Randomized Double--Blind, Placebo Controlled Clinical Trial. Kabir, Md. Anwarul; Ripa, Farhana Alam; Hasan, Mahmud // European Journal of Scientific Research;Dec2009, Vol. 38 Issue 1, p104 

    Irritable Bowel Syndrome (IBS) is a common disorder in Bangladesh. Several studies with probiotics have shown promising results in the treatment of IBS. One of the probiotics used was Saccharomyces boulardii. This is a randomized double blind placebo controlled clinical trial of S. boulardii in...

  • Review: Some therapies for treating the irritable bowel syndrome may be effective for symptom improvement.  // ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, p78 

    This article presents information related to therapies for treating the irritable bowel syndrome (IBS) which may be effective for symptom improvement. Fully published studies in the English language were selected if they were placebo-controlled studies on the treatment of IBS. 5 trials showed a...

  • FUNCTIONAL BOWEL DISORDERS.  // American Journal of Gastroenterology;Sep2005 Supplement 2, Vol. 100, pS321 

    The article presents abstracts of research papers related to functional bowel disorders. They include "The Prevalence of Constipation in Korean Population," "Cyclic Vomiting Syndrome in Adults: A Report of 41 Patients," "Visual Feedback Alters Perception of Rectal Distension in Patients with...

  • Functional Bowel Disorders in Iranian Population using Rome III Criteria. Sorouri, Majid; Pourhoseingholi, Mohammad A.; Vahedi, Mohsen; Safaee, Azadeh; Moghimi-Dehkordi, Bijan; Pourhoseingholi, Asma; Habibi, Manijeh; Zali, Mohammad R. // Saudi Journal of Gastroenterology;Jul2010, Vol. 16 Issue 3, p154 

    Background/Aim: To study the prevalence and risk factors of functional bowel disorders (FBD) in Iranian community using Rome III criteria. Materials and Methods: This study was a cross-sectional household survey conducted from May 2006 to December 2007 in Tehran province, Iran, including 18,180...

  • Excuse me, can we talk about poop? Murphree, Rodger // American Chiropractor;Sep2007, Vol. 29 Issue 9, p34 

    The article focuses on irritable bowel syndrome (IBS), that is characterized by abdominal pain or discomfort which affects 10 to 20 percent of the general population in the U.S. It stated that IBS symptoms are caused by disturbance in the interaction between the gut or the intestines, the brain...

  • Tolerability and Safety of Alosetron During Long-Term Administration in Female and Male Irritable Bowel Syndrome Patients. Wolfe, Steven G.; Chey, William Y.; Washington, Mary Kay; Harding, Jacqueline; Heath, Amy T.; McSorley, David J.; Dukes, George E.; Hunt, Christine M. // American Journal of Gastroenterology;Mar2001, Vol. 96 Issue 3, p803 

    OBJECTIVES: Alosetron (Lotronex) is a new therapeutic agent for irritable bowel syndrome (IBS) in women with diarrhea-predominant IBS. This multicenter randomized, double-blind, placebo-controlled study assessed the safety and tolerability of alosetron during long-term (≤ 12 months)...

  • Alosetron Improves Quality of Life in Women With Diarrhea-Predominant Irritable Bowel Syndrome. Watson, Maria E.; Lacey, Loretto; Kong, Steven; Northcutt, Allison R.; McSorley, David; Hahn, Beth; Mangel, Allen W. // American Journal of Gastroenterology;Feb2001, Vol. 96 Issue 2, p455 

    OBJECTIVES: The aim of this study was to assess the impact of alosetron, a treatment recently approved in the United States for irritable bowel syndrome in diarrhea-predominant female patients, on health-related quality of life. METHODS: Quality of life was assessed as part of two 12-wk...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics