Oesophageal free papers

April 2005
Gut;Apr2005 Supplement 2, Vol. 54, pA14
Academic Journal
The article presents information on abstracts related to oesophagus. In an abstract the emphasis is given on the effect of acid suppression on the proliferation status of Barrett's Oesophagus. Gastro-oesophageal reflux has been advocated as the main risk factor for the development of Barrett's oesophagus, the precursor of oesophageal adenocarcinoma (AC). Whether or not profound acid suppression has a role in the prevention of AC in patients with Barrett's oesophagus is not known. Mcm2 is a marker of proliferation. Researchers have previously shown that Mcm2 expression increases, with abnormal expression in the upper crypis and the surface epithelium, during carcinogenesis.


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