TITLE

Inflammatory bowel disease free papers

PUB. DATE
April 2005
SOURCE
Gut;Apr2005 Supplement 2, Vol. 54, pA1
SOURCE TYPE
Academic Journal
DOC. TYPE
Abstract
ABSTRACT
The article presents information on abstracts related to inflammatory bowel disease. According to a abstract amplification of toll-like receptor sensitivity by muramyl dipeptide is impaired in Crohn's disease associated NOD2 mutations. Both NOD2/CARD1 5 alleles are mutated in about 15% of Crohn's disease patients, but Functional effects remain unclear. Most studies have been performed in transfected cell lines, which may not reflect function in primary human cells, particularly interactions with toll-like receptor pathogen recognition pathways.
ACCESSION #
16567945

 

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