Clinical Experience with a New Rate-Responsive TX Pacemaker

Yasuno, Masao; Nishino, Yoshihide; Nishino, Masami; Akashi, Taizo; Tanahashi, Hideo; Kobayashi, Keiji; Yamada, Yoshio; Inoue, Michiteshi
December 1986
Angiology;Dec1986 Part 1, Vol. 37 Issue 12, p888
Academic Journal
In this report, we describe our initial experience with a new rate-responsive TX pacemaker in 10 patients. This pacemaker system uses a conventional transvenous ventricular electrode, which senses the evoked QT interval after a ventricular paced beat, as an indicator of physiological metabolic demand. Implantation of the TX pacemaker does not differ from that of conventional VVI units, and two special modes are available after implantation: TX and VVI mode. Bicycle ergometer tests showed that significantly higher rate response and exercise ability were achieved during the TX mode compared with the VVI mode (mean maximal heart rate: 115 � 13 bpm vs 96 � 21 bpm, p < 0.01, and mean maximal exercise time; 10.7 � 3.9 mm vs 8.0 � 3.8 mm, p < 0.01, respectively). In one patient, cardiac index was measured by a thermodilution method during the bicycle ergometer test, which confirmed that an adequate Increase In cardiac index (rest: 3.38 liters/min/m� , vs exercise; 7.34 liters /min/m�) was obtained by an increase of the pacing rate (rest: 72 bpm vs exercise: 128 bpm). Our results show that physiological rate-responsive pacing using the QT interval provides a simple means of increasing the heart rate and cardiac index.


Related Articles

  • Molecular Regulation and Pharmacology of Pacemaker Channels. Bois, Patrick; Guinamard, Romain; Chemaly, Antoun E.L.; Faivre, Jean-Francois; Bescond, Jocelyn // Current Pharmaceutical Design;Aug2007, Vol. 13 Issue 23, p2338 

    The spontaneous activity of cardiac tissue originates in specialized pacemaker cells in the sino-atrial node that generate autonomous rhythmic electrical impulses. A number of regions in the brain are also able to generate spontaneous rhythmic activity to control and regulate important...

  • Pacemaker Malfunction. Hayes, David L.; Vlietstra, Ronald E. // Annals of Internal Medicine;10/15/93, Vol. 119 Issue 8, p828 

    Discusses considerations in preventing pacemaker malfunction. Consequences of a pacemaker's failure; Cause of failure to capture; Environmental factors which can induce pacemaker malfunction.

  • Chronotropic incompetence in Chagas disease: effectiveness of blended sensor (volume/minute and accelerometer). Menezes Junior, Antonio da Silva; da Silva, Aline Pereira; Batista Profahl, Giovana Gurian; Ottobeli, Catarine; Silva Louzeiro, Jutay Fernando // Brazilian Journal of Cardiovascular Surgery;Jul-Sep2015, Vol. 30 Issue 3, p311 

    Introduction: Technological progress of pacemakers has allowed the association of two or more sensors in one heart rate system response. The accelerometer sensor measures the intensity of the activity; it has a relatively rapid response to the beginning of it, however, it may present...

  • Anesthetic implications for patients with rate-responsive pacemakers. Anand, Neil K.; Maguire, David P. // Seminars in Cardiothoracic & Vascular Anesthesia;Sep2005, Vol. 9 Issue 3, p251 

    One hundred thousand adults and children in the United States receive pacemakers each year, of which 85% are rate-responsive pacemakers (RRPs). Recent advances in the fields of computer programming and computer chip technology have led to the myriad development of RRPs, which contain sensors...

  • The heart beat does not make us tick: The impacts of heart rate and arousal on time perception. Schwarz, Marcus; Winkler, Isabell; Sedlmeier, Peter // Attention, Perception & Psychophysics;Jan2013, Vol. 75 Issue 1, p182 

    According to popular models of human time perception, variations in prospective timing are caused by two factors: the pulse rate of an internal pacemaker and the amount of attention directed to the passage of time. The results concerning the effect of attention on subjective timing have been...

  • The Australian and New Zealand Cardiac Pacing and Implantable Cardioverter–Defibrillator Survey: Calendar Year 2005 Mond, Harry G.; Whitlock, Ralph M.L. // Heart, Lung & Circulation;Apr2008, Vol. 17 Issue 2, p85 

    Background: A pacemaker (PM) and implantable cardioverter–defibrillator (ICD) survey was undertaken in Australia (Au) and New Zealand (NZ) for 2005. Results and Conclusions: Compared to the 2001 survey, significant increases in implantation numbers were recorded. For 2005, the total new...

  • Pacemakers: Dual or Single Chamber Implantation. Mayer, David A.; Tsapogas, Makis J. // Vascular Surgery;Jun1992, Vol. 26 Issue 5, p400 

    One hundred and seventy-five consecutive patients receiving transvenous permanent pacemakers were reviewed in a comparison of the morbidity of 70 atrioventricular (AV) implantations (DDD 60, DVI 10) and 105 ventricular implantations (WI 104, VVIR 1). Two atrial lead dislodgements occurred in the...

  • An Unusual Case of Multiple Right Atrial Thrombi in a Patient with a Dual-Chamber Pacemaker. Schifter, David R.; Kozer, Leonid M.; Saul, Barry I.; Reddy, C. V. R. // Angiology;Oct1999, Vol. 50 Issue 10, p855 

    The authors present an unusual case of multiple large atrial thrombi attached to permanent pacemaker leads identified by transesophageal echocardiography. Pathogenesis, clinical implications, and therapeutic options of pacemaker thrombi are discussed.

  • Detection of autonomic modulation in permanent atrial fibrillation. Stridh, M.; Meurling, C.; Olsson, B.; Sörnmo, L. // Medical & Biological Engineering & Computing;Nov2003, Vol. 41 Issue 6, p625 

    A new signal processing method for the detection of cyclic variations in atrial fibrillation frequency is presented. The objective was to investigate whether or not respiration, through the autonomic nervous system, modulates the fibrillation frequency in patients with permanent atrial...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics